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Folate Receptor 1

Known as: Receptor alpha, Folate, Folate Receptor alpha, Ovarian Tumor Associated Antigen MOv18 
A subtype of GPI-anchored folate receptors that is expressed in tissues of epithelial origin. This protein is also identified as an ovarian-tumor… 
National Institutes of Health

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12 relations
FOLR1 geneFOLR1 wt AlleleIn BloodProcess of secretion

Narrower (2)

FOLR1 protein, humanNeurodegeneration Due To Cerebral Folate Transport Deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
First-in-human (FIH) phase 1 (Ph1) study of MORAb-202 in patients (pts) with advanced folate receptor alpha (FRA)-positive solid tumors.
5544 Background: MORAb-202 is an antibody drug conjugate consisting of farletuzumab (a humanized monoclonal antibody that binds… 
2012
2012
The Human Folate Receptor 1 Gene: Molecular Diagnostic of Folate Deficiency
Folate is a water-soluble vitamin of the B complex group, and is required for optimal health, growth, and development. In human… 
2011
2011
IgE immunotherapy of solid tumours: a novel model targeting folate receptor alpha (FR alpha)-positiv
2010
2010
A randomized, double-blind, placebo-controlled phase II study of the efficacy and safety of farletuzumab (MORAb-003) in combination with weekly paclitaxel in subjects with platinum-resistant or…
TPS255 Background: Farletuzumab (MORAb-003) is a humanized monoclonal antibody that binds to the folate receptor alpha (FRA… 
2009
2009
EM Immunolocalization of Folate Receptor alpha (FR) and Proton-Coupled Folate Transporter (PCFT) in Retinal Müller Cells
2009
2009
The wide variation in response of mesothelioma cell lines to pemetrexed and lack of relationship to presence of folate receptor alpha (Fra).
2009
2009
Expression of folate receptor alpha (FRa) in malignant pleural mesothelioma patients by immunohistochemistry: a clinico-pathological analysis
2002
2002
Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of…
DC-3F/FA3 cells (FA3) were derived from antifolate-sensitive CHL cells by selection for growth in folate-free media containing 15… 
1999
1999
DNA vaccination against the ovarian carcinoma-associated antigen folate receptor alpha (FRalpha) induces cytotoxic T lymphocyte and antibody responses in mice.
Human folate receptor alpha (FRalpha) is a folate-binding protein that is selectively overexpressed in ovarian carcinoma and has… 
1991
1991
Preclinical pharmacokinetics and localization studies of the radioiodinated anti-ovarian carcinoma MAb MOv18.
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