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Folate Receptor 1

Known as: Receptor alpha, Folate, Folate Receptor alpha, Ovarian Tumor Associated Antigen MOv18 
A subtype of GPI-anchored folate receptors that is expressed in tissues of epithelial origin. This protein is also identified as an ovarian-tumor… 
National Institutes of Health

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12 relations
FOLR1 geneFOLR1 wt AlleleIn BloodProcess of secretion

Narrower (2)

FOLR1 protein, humanNeurodegeneration Due To Cerebral Folate Transport Deficiency

Papers overview

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2020
2020
Autistic traits and components of the folate metabolic system: an explorative analysis in the eastern Indian ASD subjects
ABSTRACT Objectives: Proper metabolism of the folate is crucial for maintaining DNA integrity, chromosome structure, methylation… 
2019
2019
First-in-human (FIH) phase 1 (Ph1) study of MORAb-202 in patients (pts) with advanced folate receptor alpha (FRA)-positive solid tumors.
5544 Background: MORAb-202 is an antibody drug conjugate consisting of farletuzumab (a humanized monoclonal antibody that binds… 
2018
2018
IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells
PurposeAccording to the American Cancer Society, 1 in 8 women in the U.S. will develop breast cancer, with triple-negative breast… 
2017
2017
Expression and characterization of the zebrafish orthologue of the human FOLR1 gene during embryogenesis.
2010
2010
A randomized, double-blind, placebo-controlled phase II study of the efficacy and safety of farletuzumab (MORAb-003) in combination with weekly paclitaxel in subjects with platinum-resistant or…
TPS255 Background: Farletuzumab (MORAb-003) is a humanized monoclonal antibody that binds to the folate receptor alpha (FRA… 
2008
2008
Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo.
2005
2005
Multivitamin and alcohol intake and folate receptor alpha expression in ovarian cancer.
Folate receptor alpha (FRalpha) expression in epithelial ovarian cancer may be related to folate intake. We examined this… 
2002
2002
Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of…
DC-3F/FA3 cells (FA3) were derived from antifolate-sensitive CHL cells by selection for growth in folate-free media containing 15… 
1999
1999
DNA vaccination against the ovarian carcinoma-associated antigen folate receptor alpha (FRalpha) induces cytotoxic T lymphocyte and antibody responses in mice.
Human folate receptor alpha (FRalpha) is a folate-binding protein that is selectively overexpressed in ovarian carcinoma and has… 
1991
1991
Preclinical pharmacokinetics and localization studies of the radioiodinated anti-ovarian carcinoma MAb MOv18.
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