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Folate Receptor 1

Known as: Receptor alpha, Folate, Folate Receptor alpha, Ovarian Tumor Associated Antigen MOv18 
A subtype of GPI-anchored folate receptors that is expressed in tissues of epithelial origin. This protein is also identified as an ovarian-tumor… Expand
National Institutes of Health

Papers overview

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2013
2013
OBJECTIVE Based on its expression profile, folate receptor alpha (FRA) is an attractive candidate for targeted diagnostics and… Expand
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Highly Cited
2012
Highly Cited
2012
Given that several targeted therapies directed towards folate receptor alpha (FRA) are in late stage clinical development, the… Expand
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Highly Cited
2010
Highly Cited
2010
Poor folate status during pregnancy can lead to elevated maternal plasma levels of homocysteine (Hcy) with associated pregnancy… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES Folate receptor alpha (FRalpha) is a folate-binding protein overexpressed on ovarian and several other epithelial… Expand
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Highly Cited
2008
Highly Cited
2008
Folate deficiency may affect gene expression by disrupting DNA methylation patterns or by inducing base substitution, DNA breaks… Expand
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Highly Cited
2008
Highly Cited
2008
Reduced derivatives of folic acid (folates) play a critical role in the development, function and repair of the CNS. However, the… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Folate metabolism pathway genes have been examined for association with neural tube defects (NTDs) because folic acid… Expand
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2006
2006
PURPOSE Studies have demonstrated that the generation of immunity to tumor antigens is associated with improved prognosis for… Expand
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Highly Cited
2003
Highly Cited
2003
The practical application of gene therapy as a treatment for cystic fibrosis is limited by poor gene transfer efficiency with… Expand
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Highly Cited
2000
Highly Cited
2000
The differential polarized distribution of the reduced- folate transporter (RFT-1) and folate receptor alpha (FRalpha), the two… Expand
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