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FOLR1 gene

Known as: Folate Receptor 1 (Adult) Gene, FOLR1, FOLATE RECEPTOR 1, ADULT 
This gene is involved in the mediation of 5-methyltetrahydrofolate delivery to the cellular interior.
National Institutes of Health

Related topics

Related topics

10 relations
FOLR1 protein, humanFOLR2 geneFOLR2 wt AlleleFOLR3 gene

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FOLR1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia.
Protection of small interfering RNA (siRNA) against degradation and targeted delivery across the plasma and endosomal membranes… 
2016
2016
Characterization and evaluation of a folic acid receptor-targeted cyclodextrin complex as an anticancer drug delivery system.
2014
2014
Effect of receptor occupancy on folate receptor internalization.
The folate receptor (FR) is a GPI anchored cell surface glycoprotein that functions to facilitate folic acid uptake and mediate… 
Highly Cited
2011
Highly Cited
2011
Folate receptor-targeted aggregation-enhanced near-IR emitting silica nanoprobe for one-photon in vivo and two-photon ex vivo fluorescence bioimaging.
A two-photon absorbing (2PA) and aggregation-enhanced near-infrared (NIR) emitting pyran derivative, encapsulated in and… 
Highly Cited
2010
Highly Cited
2010
Synthesis and in vitro evaluation of defined HPMA folate conjugates: influence of aggregation on folate receptor (FR) mediated cellular uptake.
In this article we report the synthesis and in vitro evaluation of well-defined, folate functionalized and fluorescently labeled… 
2009
2009
(177)Lu- labeled MOv18 as compared to (131)I- or (90)Y-labeled MOv18 has the better therapeutic effect in eradication of alpha folate receptor-expressing tumor xenografts.
Highly Cited
2008
Highly Cited
2008
4001 Short Report
  • 2008
  • Corpus ID: 18978472
Introduction Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are directly targeted to the apical domain of the… 
Highly Cited
2003
Highly Cited
2003
Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate.
Fluorescence optical imaging technologies are currently being developed to image specific molecular targets in vivo. Detection… 
Highly Cited
2001
Highly Cited
2001
Folate receptor function is regulated in response to different cellular growth rates in cultured mammalian cells.
The folate receptor (FR) binds physiologic folates with nmol/L affinities and is expected to play an important role in… 
1993
1993
Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene.
The primary structures of the human KB cell (FR-KB1) folate receptor (FR) and of a human placental (FR-P2) FR, proteins important… 
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