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Focal Adhesions

Known as: Plaques, Adhesion, Adherens Junctions, Cell-Matrix, Cell to matrix adherens junction 
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN… Expand
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Recent progress in the design and application of artificial cellular microenvironments and nanoenvironments has revealed the… Expand
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Highly Cited
2001
Highly Cited
2001
Mechanical forces play a major role in the regulation of cell adhesion and cytoskeletal organization. In order to explore the… Expand
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Review
1997
Review
1997
  • R. Pelham, Y. Wang
  • Proceedings of the National Academy of Sciences…
  • 1997
  • Corpus ID: 6813719
Responses of cells to mechanical properties of the adhesion substrate were examined by culturing normal rat kidney epithelial and… Expand
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Review
1996
Review
1996
Focal adhesions are sites of tight adhesion to the underlying extracellular matrix developed by cells in culture. They provided a… Expand
Highly Cited
1996
Highly Cited
1996
Activated rhoA, a ras-related GTP-binding protein, stimulates the appearance of stress fibers, focal adhesions, and tyrosine… Expand
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Highly Cited
1995
Highly Cited
1995
THE intracellular protein tyrosine kinase FAK (focal adhesion kinase) was originally identified by its high level of tyrosine… Expand
Highly Cited
1995
Highly Cited
1995
Rho and rac, two members of the ras-related superfamily of small GTPases, regulate the polymerization of actin to produce stress… Expand
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Highly Cited
1992
Highly Cited
1992
Actin stress fibers are one of the major cytoskeletal structures in fibroblasts and are linked to the plasma membrane at focal… Expand
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Highly Cited
1992
Highly Cited
1992
Expression of the Rous sarcoma virus-encoded oncoprotein, pp60v-src, subverts the normal regulation of cell growth, which results… Expand
Review
1988
Review
1988
INTRODUCTION 487 MORPHOLOGY AND OBSERVATION OF FOCAL ADHESIONS 488 FORMATION OF FOCAL ADHESIONS 490 DYNAMICS OF FOCAL ADHESION… Expand
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