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Focal Adhesions

Known as: Plaques, Adhesion, Adherens Junctions, Cell-Matrix, Cell to matrix adherens junction 
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Mechanical forces are central to developmental, physiological and pathological processes. However, limited understanding of force… Expand
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Review
2009
Review
2009
Recent progress in the design and application of artificial cellular microenvironments and nanoenvironments has revealed the… Expand
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Review
2004
Review
2004
Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin cytoskeleton. Cells modify focal adhesions… Expand
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Highly Cited
2001
Highly Cited
2001
Mechanical forces play a major role in the regulation of cell adhesion and cytoskeletal organization. In order to explore the… Expand
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Highly Cited
1997
Highly Cited
1997
The small guanosine triphosphatase (GTPase) Rho is implicated in the formation of stress fibers and focal adhesions in… Expand
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Review
1996
Review
1996
Focal adhesions are sites of tight adhesion to the underlying extracellular matrix developed by cells in culture. They provided a… Expand
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Highly Cited
1996
Highly Cited
1996
Activated rhoA, a ras-related GTP-binding protein, stimulates the appearance of stress fibers, focal adhesions, and tyrosine… Expand
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Highly Cited
1995
Highly Cited
1995
THE intracellular protein tyrosine kinase FAK (focal adhesion kinase) was originally identified by its high level of tyrosine… Expand
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Highly Cited
1992
Highly Cited
1992
Actin stress fibers are one of the major cytoskeletal structures in fibroblasts and are linked to the plasma membrane at focal… Expand
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Review
1988
Review
1988
INTRODUCTION 487 MORPHOLOGY AND OBSERVATION OF FOCAL ADHESIONS 488 FORMATION OF FOCAL ADHESIONS 490 DYNAMICS OF FOCAL ADHESION… Expand
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