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Fleroxacin
Known as:
Fleroxacin [Chemical/Ingredient]
, Fleroxacinum
, 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
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A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
National Institutes of Health
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Related topics
Related topics
16 relations
Narrower (5)
AM-833
Megalone (TN)
Quinodis
Ro 23-6240
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Broader (2)
Anti-Infective Agents
Topoisomerase II Inhibitors
Fleroxacin:Susc:Pt:Isolate:OrdQn
Fleroxacin:Susc:Pt:Isolate:OrdQn:MIC
In Blood
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Spectrofluorimetric study of the charge-transfer complexation of certain fluoroquinolones with 7,7,8,8-tetracyanoquinodimethane.
L. Du
,
H. Yao
,
Mingkai Fu
Spectrochimica Acta Part A - Molecular and…
2005
Corpus ID: 21526338
1999
1999
Comparative studies of modulatory effect to the function of rat peritoneal neutrophils treated with new quinolones.
Y. Azuma
,
P. Wang
,
+4 authors
K. Ohura
Immunology Letters
1999
Corpus ID: 12230675
Highly Cited
1998
Highly Cited
1998
Photocleavage of DNA by the fluoroquinolone antibacterials.
Lydia Martinez
,
Colin F. Chignell
Journal of Photochemistry and Photobiology. B…
1998
Corpus ID: 10101354
1993
1993
Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography
A. Fischman
,
E. Livni
,
+7 authors
H. Strauss
Antimicrobial Agents and Chemotherapy
1993
Corpus ID: 37395993
Positron emission tomography (PET) with [18F]fleroxacin was used to study the pharmacokinetics of fleroxacin, a new broad…
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1993
1993
Comparative efficacy and safety of oral fleroxacin and amoxicillin/clavulanate potassium in skin and soft tissue infections.
H. Tassler
American Journal of Medicine
1993
Corpus ID: 40440171
The objective of this open-label, randomized, multicenter study was to compare the efficacy and safety of fleroxacin, 400 mg…
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Review
1992
Review
1992
Fleroxacin Clinical Pharmacokinetics
A. Stuck
,
Donbosco K. Kim
,
F. Frey
Clinical Pharmacokinetics
1992
Corpus ID: 9949453
SummaryFleroxacin is a new member of the class of fluoroquinolones. The drug has good activity (i.e. minimum inhibitory…
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1991
1991
Antimicrobial activity evaluations of two new quinolones, PD127391 (CI-960 and AM-1091) and PD131628.
M. Barrett
,
R. Jones
,
M. Erwin
,
D. M. Johnson
,
B. Briggs
Diagnostic microbiology and infectious disease
1991
Corpus ID: 32263875
1988
1988
Multicenter in vitro evaluation of lomefloxacin (NY-198, SC-47111), including tests against nearly 7,000 bacterial isolates and preliminary recommendations for susceptibility testing.
R. Jones
,
K. Aldridge
,
+4 authors
J. Washington
Diagnostic microbiology and infectious disease
1988
Corpus ID: 26041566
1988
1988
Pharmacokinetics and body fluid penetration of fleroxacin in healthy volunteers.
F. Sorgel
,
R. Metz
,
K. Naber
,
R. Seelmann
,
P. Muth
Journal of Antimicrobial Chemotherapy
1988
Corpus ID: 36243079
The pharmacokinetics of fleroxacin after oral administration of 400 mg fleroxacin in twelve healthy volunteers were investigated…
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1988
1988
Single and multiple dose pharmacokinetics of fleroxacin.
E. Weidekamm
,
R. Portmann
,
C. Partos
,
D. Dell
Journal of Antimicrobial Chemotherapy
1988
Corpus ID: 26270623
Pharmacokinetics of fleroxacin following single and multiple dosing were studied in healthy male volunteers. The characteristics…
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