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Fleroxacin

Known as: Fleroxacin [Chemical/Ingredient], Fleroxacinum, 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid 
A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
This study developed a method for analysis of nineteen quinolone and fluoroquinolone antibiotics (FQs) in sludge samples, and… Expand
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Highly Cited
2011
Highly Cited
2011
Water samples were collected from 19 sampling sites along the Huangpu River in June and December 2009. The occurrence… Expand
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Highly Cited
2010
Highly Cited
2010
The residue levels of selected fluoroquinolones, sulfonamides and tetracyclines in 143 animal dung samples collected in 2007 from… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Oral combination therapy with fluoroquinolones plus rifampicin is a promising alternative to standard parenteral… Expand
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2001
2001
Abstract. Quinolone therapy can be associated with tendon disorders (tendinitis, ruptures), but little is known about possible… Expand
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Review
1999
Review
1999
Reactions of the gastrointestinal tract, the CNS and the skin are the most often observed adverse effects during therapy with… Expand
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1997
1997
BACKGROUND There have been few reports concerning the cytotoxic effects of fluoroquinolone antibiotics on transitional cell… Expand
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Review
1995
Review
1995
Resistance of Neisseria gonorrhoeae to antimicrobial agents continues to spread and intensify. Choosing an antimicrobial regimen… Expand
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1994
1994
Scanning confocal laser microscopy (SCLM) and fluorescent molecular probes were used to evaluate the effect of the… Expand
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Highly Cited
1988
Highly Cited
1988
The uptake of quinolone antibiotics by Escherichia coli was investigated by using fleroxacin (RO 23-6240, AM 833) as a prototype… Expand
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