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Filgrastim

Known as: R metHuG CSF, R-metHuG-CSF, Filgrastim XM02 
A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating… 
National Institutes of Health

Related topics

Related topics

29 relations
0.8 ML FILGRASTIM-SNDZ 0.6 MG/ML Prefilled Syringe0.8 ML Filgrastim 0.6 MG/ML Prefilled Syringe [Neupogen]1 ML Filgrastim 0.3 MG/ML Injection [Neupogen]CSF3 gene

Broader (3)

Colony-Stimulating FactorsHematologic AgentsRecombinant Proteins

Narrower (3)

NeupogenTopneuterZarxio

Papers overview

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Highly Cited
2006
Highly Cited
2006
Tissue distribution of 18F-FDG-labeled peripheral hematopoietic stem cells after intracoronary administration in patients with myocardial infarction.
UNLABELLED Adult stem cell therapy is expected to improve left ventricular function in patients with myocardial infarction… 
Highly Cited
2000
Highly Cited
2000
Randomized, dose-escalation study of SD/01 compared with daily filgrastim in patients receiving chemotherapy.
PURPOSE To explore the use of SD/01 (a polyethylene glycol-conjugated filgrastim shown in preclinical studies to have a prolonged… 
Review
1998
Review
1998
Anti‐inflammatory effects of granulocyte colony‐stimulating factor
The innate, unspecific immune response to bacterial and fungal infection is mediated primarily by neutrophilic granulocytes… 
Highly Cited
1997
Highly Cited
1997
Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and…
PURPOSE Thrombocytopenia may compromise cancer treatment, causing chemotherapy dose reductions, schedule alterations, or the need… 
Highly Cited
1995
Highly Cited
1995
Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division.
It is known that the majority of primitive hematopoietic progenitors are in a noncycling quiescent state. In addition, normal… 
Highly Cited
1994
Highly Cited
1994
Concomitant in vivo production of 19 different cytokines in human tonsils.
Accumulating data indicate that cytokines, peptides involved in regulation of both physiological and pathological immune… 
Highly Cited
1993
Highly Cited
1993
Regulation of neutrophil-derived IL-8: the role of prostaglandin E2, dexamethasone, and IL-4.
Historically, the neutrophil has been perceived as a terminally differentiated leukocyte with limited ability to produce de novo… 
Highly Cited
1991
Highly Cited
1991
Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells.
Various growth factors are known to stimulate both early and late stages of human hematopoietic cell development in semisolid… 
Highly Cited
1988
Highly Cited
1988
Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte…
Interleukin 1 alpha (IL-1 alpha), tumor necrosis factor alpha (TNF alpha), granulocyte-colony-stimulating factor (G-CSF), and… 
Highly Cited
1987
Highly Cited
1987
Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide.
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