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Filgrastim

Known as: R metHuG CSF, R-metHuG-CSF, Filgrastim XM02 
A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating… 
National Institutes of Health

Related topics

Related topics

29 relations
0.8 ML FILGRASTIM-SNDZ 0.6 MG/ML Prefilled Syringe0.8 ML Filgrastim 0.6 MG/ML Prefilled Syringe [Neupogen]1 ML Filgrastim 0.3 MG/ML Injection [Neupogen]CSF3 gene

Broader (3)

Colony-Stimulating FactorsHematologic AgentsRecombinant Proteins

Narrower (3)

NeupogenTopneuterZarxio

Papers overview

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Highly Cited
2002
Highly Cited
2002
Erythropoietin and G-csf Receptors in Human Tumor Cells: Expression and Aspects regarding Functionality
Aims and Background Recombinant human erythropoietin (Epo) and granulocyte-colony-stimulating factor (G-CSF) are used to… 
Highly Cited
2000
Highly Cited
2000
Paclitaxel and cisplatin in advanced or recurrent carcinoma of the endometrium: long-term results of a phase II multicenter study.
OBJECTIVES Both paclitaxel and cisplatin have moderate activity in patients with metastatic or recurrent carcinoma of the… 
Highly Cited
1999
Highly Cited
1999
Combined irinotecan and oxaliplatin plus granulocyte colony-stimulating factor in patients with advanced fluoropyrimidine/leucovorin-pretreated colorectal cancer.
PURPOSE To evaluate the efficacy and tolerance of combined irinotecan and oxaliplatin in patients with advanced colorectal cancer… 
Highly Cited
1999
Highly Cited
1999
Functional and molecular analysis of hematopoietic progenitors derived from the aorta-gonad-mesonephros region of the mouse embryo.
Herein, we show that CD34, c-kit double-positive (CD34(+)c-kit(+)) cells from the aorta-gonad-mesonephros (AGM) region of the… 
Highly Cited
1998
Highly Cited
1998
First-line treatment of advanced non-small-cell lung cancer with docetaxel and cisplatin: a multicenter phase II study.
PURPOSE To evaluate the efficacy and safety of the docetaxel-cisplatin combination in patients with advanced non-small-cell lung… 
Review
1996
Review
1996
Use of hematopoietic colony-stimulating factors: the American Society of Clinical Oncology survey. The Health Services Research Committee of the American Society of Clinical Oncology.
PURPOSE Dissemination of use of the hematopoietic colony-stimulating factors (CSFs) is unprecedented in oncology, with almost all… 
Highly Cited
1996
Highly Cited
1996
Tryptophan 650 of human granulocyte colony-stimulating factor (G-CSF) receptor, implicated in the activation of JAK2, is also required for G-CSF-mediated activation of signaling complexes of the…
Granulocyte colony-stimulating factor (G-CSF) induces rapid phosphorylation of JAK kinases as well as activation of the p21ras… 
Highly Cited
1991
Highly Cited
1991
Characterization of cytokine production by the metrial gland and granulated metrial gland cells.
Highly Cited
1989
Highly Cited
1989
Effects of recombinant growth factors on radiation survival of human bone marrow progenitor cells.
Highly Cited
1989
Highly Cited
1989
Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture.
Previous in vitro investigations on enriched human hematopoietic progenitors have led to the conclusion that the purified… 
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