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Filgrastim

Known as: R metHuG CSF, R-metHuG-CSF, Filgrastim XM02 
A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating… 
National Institutes of Health

Related topics

Related topics

29 relations
0.8 ML FILGRASTIM-SNDZ 0.6 MG/ML Prefilled Syringe0.8 ML Filgrastim 0.6 MG/ML Prefilled Syringe [Neupogen]1 ML Filgrastim 0.3 MG/ML Injection [Neupogen]CSF3 gene

Broader (3)

Colony-Stimulating FactorsHematologic AgentsRecombinant Proteins

Narrower (3)

NeupogenTopneuterZarxio

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone.
Hematopoietic progenitor cells (HPCs) traffic to and are retained in the marrow through the trophic effects of the chemokine… 
Review
2004
Review
2004
Regulation of myeloid development and function by colony stimulating factors.
Highly Cited
2002
Highly Cited
2002
Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils.
In vitro studies as well as clinical trials indicate that the cytokines granulocyte-macrophage colony-stimulating factor (GM-CSF… 
Highly Cited
2001
Highly Cited
2001
Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor.
Mobilized progenitor cells currently represent the most commonly used source of hematopoietic progenitor cells (HPCs) to effect… 
Highly Cited
2000
Highly Cited
2000
Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells.
Peripheral blood stem cells (PBSC) obtained from granulocyte-colony stimulating factor (G-CSF)-mobilized donors are increasingly… 
Review
1994
Review
1994
Paclitaxel. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer.
Paclitaxel is a new anticancer agent with a novel mechanism of action. It promotes polymerisation of tubulin dimers to form… 
Highly Cited
1991
Highly Cited
1991
Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.
The cDNA for human stem cell factor (hSCF) has been cloned and expressed in mammalian and bacterial hosts and recombinant protein… 
Highly Cited
1987
Highly Cited
1987
Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells
A panning method has been developed to enrich Langerhans cells (LC) from murine epidermis. In standard culture media, the… 
Highly Cited
1987
Highly Cited
1987
Synergy of interleukin 1 and granulocyte colony-stimulating factor: in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-fluorouracil treatment of mice.
The human bladder carcinoma cell line 5637 produces hematopoietic growth factors [granulocyte and granulocyte/macrophage colony… 
Highly Cited
1987
Highly Cited
1987
Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line.
Human granulocyte colony stimulating factor (G-CSF) can support the survival and short term proliferation of the interleukin 3… 
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