Fentanyl

Known as: 1-Phenethyl-4-(N-phenylpropionamido)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide, Fentanyl CII 
A synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in… (More)

Topic mentions per year

Topic mentions per year

1958-2017
050019582017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The United States is experiencing an epidemic of drug overdose (poisoning) deaths. Since 2000, the rate of deaths from drug… (More)
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Highly Cited
2009
Highly Cited
2009
CONTEXT Gamma-aminobutyric acid receptor agonist medications are the most commonly used sedatives for intensive care unit (ICU… (More)
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Highly Cited
2008
Highly Cited
2008
SUMMARY OF CONSENSUS: 1. The use of opioids in cancer pain: The criteria for selecting analgesics for pain treatment in the… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Untreated, one third of patients who undergo surgery will have postoperative nausea and vomiting. Although many trials… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND It has been reported that mu-opioid receptor activation leads to a sustained increase in glutamate synaptic… (More)
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Highly Cited
1999
Highly Cited
1999
PURPOSE In a randomized, double-blind clinical trial, we compared the postoperative analgesic effect and dose consumption of… (More)
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Highly Cited
1998
Highly Cited
1998
Opioid drugs play important roles in the clinical management of pain, as well as in the development and treatment of drug abuse… (More)
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Highly Cited
1990
Highly Cited
1990
More than 80 deaths have occurred after the use of midazolam (Versed), often in combination with opioids, to sedate patients… (More)
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Highly Cited
1987
Highly Cited
1987
In a randomised controlled trial, preterm babies undergoing ligation of a patent ductus arteriosus were given nitrous oxide and d… (More)
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Highly Cited
1980
Highly Cited
1980
Fentanyl is considered to be a short-acting narcotic analgesic but prolonged and recurrent ventilatory depression has been… (More)
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