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Fentanyl

Known as: 1-Phenethyl-4-(N-phenylpropionamido)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide, Fentanyl CII 
A synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
The U.S. opioid epidemic is continuing, and drug overdose deaths nearly tripled during 1999-2014. Among 47,055 drug overdose… 
Highly Cited
2000
Highly Cited
2000
Background It has been reported that &mgr;-opioid receptor activation leads to a sustained increase in glutamate synaptic… 
Highly Cited
1999
Highly Cited
1999
PurposeIn a randomized, double-blind clinical trial, we compared the postoperative analgesic effect and dose consumption of… 
Highly Cited
1990
Highly Cited
1990
More than 80 deaths have occurred after the use of midazolam (Versed), often in combination with opioids, to sedate patients… 
Highly Cited
1989
Highly Cited
1989
Fentanyl was administered intravenously and transdermally to eight surgical patients to determine the systemic bioavailability… 
Highly Cited
1987
Highly Cited
1987
  • J. Scott, D. Stanski
  • The Journal of pharmacology and experimental…
  • 1987
  • Corpus ID: 25168991
The effect of increasing age on the dose of fentanyl or alfentanil required to produce the same electroencephalographic (EEG… 
Highly Cited
1985
Highly Cited
1985
Fentanyl and alfentanil produce very similar electroencephalographic (EEG) changes in humans. With increasing serum… 
Review
1983
Review
1983
  • L. Mather
  • Clinical pharmacokinetics
  • 1983
  • Corpus ID: 27762787
Fentanyl, a synthetic opiate with a (clinical) potency of 50 to 100 times that of morphine, was introduced into clinical practice… 
Highly Cited
1980
Highly Cited
1980
Fentanyl is considered to be a short‐acting narcotic analgesic but prolonged and recurrent ventilatory depression has been…