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Factor XIa

Known as: XIa, Coagulation Factor, Activated Factor XI, Blood Coagulation Factor XI, Activated 
Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR… 
National Institutes of Health

Related topics

Related topics

9 relations
CoagulantsProcess of secretionagonistsantagonists & inhibitors

Broader (1)

Factor XI

Papers overview

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Highly Cited
2018
Highly Cited
2018
Two-Dimensional-Layered Perovskite ALaTa2O7:Bi3+ (A = K and Na) Phosphors with Versatile Structures and Tunable Photoluminescence.
Topological chemical reaction methods are indispensable for fabricating new materials or optimizing their functional properties… 
Review
2016
Review
2016
Factor XIa inhibitors: A review of the patent literature
ABSTRACT Introduction: Anticoagulants are the mainstay for prevention and/or treatment of thrombotic disorders. Each clinically… 
Highly Cited
2012
Highly Cited
2012
Explicit symplectic multidimensional exponential fitting modified Runge-Kutta-Nyström methods
This paper is concerned with multidimensional exponential fitting modified Runge-Kutta-Nyström (MEFMRKN) methods for the system… 
Highly Cited
2009
Highly Cited
2009
Flow patterns in the sedimentation of an elliptical particle
We study the dynamics of a single two-dimensional elliptical particle sedimenting in a Newtonian fluid using numerical… 
2009
2009
Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor.
Heparin accelerates inhibition of factor XIa (fXIa) by the serpins antithrombin (AT) and C1-inhibitor (C1-INH) by more than 2… 
Highly Cited
2005
Highly Cited
2005
Antibacterial effects of the Cu(II)-exchanged montmorillonite on Escherichia coli K88 and Salmonella choleraesuis.
Highly Cited
2005
Highly Cited
2005
Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2*
Factor XIa (FXIa) is a serine protease important for initiating the intrinsic pathway of blood coagulation. Protease nexin 2 (PN2… 
Highly Cited
2002
Highly Cited
2002
Unusual Proteolytic Activation of Pro-hepatocyte Growth Factor by Plasma Kallikrein and Coagulation Factor XIa*
Hepatocyte growth factor (HGF), the ligand for the receptor tyrosine kinase c-Met, is composed of an α-chain containing four… 
Highly Cited
1998
Highly Cited
1998
Using Kohonen's Self-Organizing Feature Map to Uncover Automobile Bodily Injury Claims Fraud
Claims fraud is an increasingly vexing problem confronting the insurance industry. In this empirical study, we apply Kohonen's… 
Highly Cited
1995
Highly Cited
1995
Inactivation of factor XIa in human plasma assessed by measuring factor XIa-protease inhibitor complexes: major role for C1-inhibitor.
From experiments with purified proteins, it has been concluded that factor XIa (FXIa) is inhibited in plasma mainly by alpha 1… 
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