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FTY 720P

Known as: FTY720-P, FTY720P, FTY720 phosphate 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

OrganophosphatesSphingosine
analogs & derivatives

Papers overview

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2018
2018
Secretome analysis of nerve repair mediating Schwann cells reveals Smad‐dependent trophism
Schwann cells promote nerve regeneration by adaptation of a regenerative phenotype referred to as repair mediating Schwann cell… 
2016
2016
Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in…
FTY720 sequesters lymphocytes in secondary lymphoid organs through effects on sphingosine-1-phosphate (S1P) receptors. However… 
2016
2016
Endocytosis of Ligand‐Activated Sphingosine 1‐Phosphate Receptor 1 Mediated by the Clathrin‐Pathway
The sphingosine 1‐phosphate receptor 1 (S1PR1) is one of five G protein‐coupled receptors activated by the lipid sphingosine 1… 
2015
2015
Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720.
2012
2012
Fingolimod impedes Schwann cell-mediated myelination: implications for the treatment of immune neuropathies?
BACKGROUND Fingolimod (FTY720), a first-in-class sphingosine-1-phosphate (S1P) receptor agonist, is a recently approved drug for… 
Highly Cited
2010
Highly Cited
2010
Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells*
We demonstrate here that the bioactive lipid sphingosine 1-phosphate (S1P) uses sphingosine 1-phosphate receptor 4 (S1P4) and… 
Highly Cited
2010
Highly Cited
2010
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate.
Hypogelsolinemia is observed in patients with different states of acute or chronic inflammation such as sepsis, rheumatoid… 
2008
2008
A splicing isoform of LPP1, LPP1a, exhibits high phosphatase activity toward FTY720 phosphate.
Highly Cited
2007
Highly Cited
2007
FTY720‐phosphate is dephosphorylated by lipid phosphate phosphatase 3
2004
2004
Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells.
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