FTY 720P

Known as: FTY720-P, FTY720P, FTY720 phosphate 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720… (More)
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2009
2009
Novel immunomodulatory molecule FTY720 is a synthetic analog of myriocin, but unlike myriocin FTY720 does not inhibit serine… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The oral immunomodulator FTY720 has shown efficacy in patients with relapsing multiple sclerosis (MS). FTY720… (More)
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Highly Cited
2007
Highly Cited
2007
Sphingosine 1-phosphate (S1P), a multifunctional lipid mediator, regulates lymphocyte trafficking, vascular permeability, and… (More)
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Highly Cited
2007
Highly Cited
2007
FTY720 [2-amino-2-[2-(4-octylphenyl) ethyl]propane-1,3-diol hydrochloride] is an oral sphingosine-1-phosphate receptor modulator… (More)
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Highly Cited
2007
Highly Cited
2007
Sphingosine-1-phosphate receptors (S1P1-5) are activated by the endogenous agonist S1P and are expressed in the central nervous… (More)
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Highly Cited
2006
Highly Cited
2006
FTY720, a potent immunomodulator, becomes phosphorylated in vivo (FTY-P) and interacts with sphingosine-1-phosphate (S1P… (More)
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Highly Cited
2005
Highly Cited
2005
Sphingosine 1-phosphate (S1P) is a lysophospholipid that exerts a variety of responses in cells such as proliferation, migration… (More)
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Highly Cited
2005
Highly Cited
2005
Sphingosine-1-phosphate (S1P) is an endogenous agonist for a family of five G protein-coupled receptors (S1P(1-5)) involved in… (More)
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Highly Cited
2004
Highly Cited
2004
FTY720 is a prodrug for FTY-phosphate, an agonist at four of the five known receptors for sphingosine-1-phosphate (S1P). We show… (More)
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