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FR 900452

Known as: FR-900452 
National Institutes of Health

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IndolesPiperazines

Papers overview

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1995
1995
Platelet-activating factor (PAF)-like phospholipids formed during peroxidation of phosphatidylcholines from different foodstuffs.
Previously, we reported that induction of peroxidation of synthetic phosphatidylcholines (PCs) containing a polyunsaturated fatty… 
1995
1995
Similar coronary vascular effects in the rat perfused heart of platelet‐activating factor structural analogues with agonist and antagonist properties
1 Selective blockade of platelet‐activating factor (PAF) receptor subtypes by PAF receptor antagonists has been demonstrated… 
1991
1991
Differential actions of platelet‐activating factor (PAF) receptor antagonists on the vasodilator and vasoconstrictor effects of PAF in the rat perfused heart
Selectivity for blocking the coronary vasodilator and vasoconstrictor effects of platelet‐activating factor (PAF) in the rat… 
1988
1988
Augmentation of DNA synthesis in guinea pig bone marrow cells by platelet-activating factor (PAF).
1988
1988
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
1986
1986
FR-900452, a specific antagonist of platelet activating factor (PAF) produced by Streptomyces phaeofaciens. I. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.
A PAF antagonist, designated as FR-900452, was isolated from fermentation products of Streptomyces phaeofaciens and the molecular… 
1986
1986
Platelet activating factor (PAF) involvement in endotoxin-induced thrombocytopenia in rabbits: studies with FR-900452, a specific inhibitor of PAF.
1986
1986
Studies of platelet activating factor (PAF) antagonists from microbial products. III. Pharmacological studies of FR-900452 in animal models.
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