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FR 180204

Known as: FR-180204, FR180204 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

PyrazolesPyridazines

Papers overview

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2020
2020
Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats
Osteoarthritis (OA) is the most prevalent joint disease and uncontrolled inflammation is now recognized to play vital roles in OA… 
2019
2019
Silver nanoparticles inhibit beige fat function and promote adiposity
2017
2017
Ciproxifan, a histamine H3 receptor antagonist and inverse agonist, presynaptically inhibits glutamate release in rat hippocampus
Highly Cited
2015
Highly Cited
2015
Novel combination of docetaxel and thymoquinone induces synergistic cytotoxicity and apoptosis in DU-145 human prostate cancer cells by modulating PI3K–AKT pathway
BackgroundThe treatment of castrate-resistant prostate cancer (CRPC) still remains as an important challenge of daily oncology… 
2015
2015
Activation of MEK/ERK pathways through NF-κB activation is involved in interleukin-1β-induced cyclooxygenease-2 expression in canine dermal fibroblasts.
2015
2015
Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells
Mucus hypersecretion by airway epithelium is a hallmark of inflammation in allergic asthma and results in airway narrowing and… 
2015
2015
Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia.
2012
2012
Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma
Highly Cited
2011
Highly Cited
2011
Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A.
2009
2009
Multi-gram scale synthesis of FR180204.
A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps… 
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