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FR 167653

Known as: FR167653 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background:Recent studies have implicated the activation of stress-activated mitogen-activated protein kinase (MAPK) p38 in… 
Highly Cited
2007
Highly Cited
2007
The objective is to assess the effect of TNF-α inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar… 
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE p38 MAP kinase (p38 MAPK) and c-Jun NH2-terminal kinase (JNK) have been implicated in the pathophysiology of heart… 
Highly Cited
2005
Highly Cited
2005
Podocytes play an important role in maintaining normal glomerular function and structure, and podocyte injury leads to… 
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE FR167653 is a potent inhibitor of p38 mitogen-activated protein kinase (MAPK) and inhibits tumor necrosis factor alpha… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND Various types of chemokines/cytokines play important roles in ischaemia/reperfusion injury in kidneys. However, the… 
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Highly Cited
2001
Highly Cited
2001
FR167653 was discovered as a cytokine production inhibitor, but its target molecule has remained unclear. We examined the effect… 
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Highly Cited
2000
Highly Cited
2000
Abstract—p38 mitogen-activated protein kinase (MAPK) is involved in intracellular signals that regulate a variety of cellular… 
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Highly Cited
1999
Highly Cited
1999
Roles of enterobacteria, nitric oxide (NO) and neutrophil in indomethacin-induced small intestinal lesions were examined in rats… 
Highly Cited
1996
Highly Cited
1996
FR167653 (1-[7-(4-fluorophenyl)-1,2,3,4-tetrahydro-8-(4-pyridyl)pyrazolo[5-1-c] [1,2,4]triazin-2-yl]-2-phenylethanedione sulfate…