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FR 167653

Known as: FR167653 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (5)

Anti-Inflammatory Agents, Non-SteroidalGrowth InhibitorsImmunosuppressive AgentsPyrazoles

Papers overview

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2008
2008
A p38 mitogen-activated protein kinase inhibitor protects against renal damage in a non-heart-beating donor model.
Ischemia-reperfusion injury is one of the central nonimmunologic processes involved in renal allograft dysfunction. Kidneys from… 
2004
2004
EFFECTS OF ANTI-INFLAMMATORY CYTOKINE AGENT (FR167653) AND SERINE PROTEASE INHIBITOR ON WARM ISCHEMIA-REPERFUSION INJURY OF THE LIVER GRAFT
Background. The shortage of donors has become a serious problem. Some institutes have tried to use grafts retrieved from non… 
2004
2004
Spermine-Induced Maturation in Wistar Rat Intestine: A Cytokine-Dependent Mechanism
Objectives: Polyamines are of great importance in biologic processes such as cell proliferation and differentiation. The… 
2004
2004
Effects of adding P38 mitogen-activated protein-kinase inhibitor to celsior solution in canine heart transplantation from non–heart-beating donors
Background. The activation of p38 mitogen-activated protein kinase (MAPK) plays an important role in ischemia-reperfusion injury… 
2002
2002
Attenuation of renal ischemia-reperfusion injury by FR167653 in dogs.
BACKGROUND Inflammatory cytokines are known to contribute to ischemia-reperfusion injury. We investigated the effect of FR167653… 
2002
2002
Effect of FR167653, a Novel Inhibitor of Tumor Necrosis Factor-&agr; and Interleukin-1&bgr; Synthesis on Lipopolysaccharide-Induced Hepatic Microvascular Dysfunction in Mice
Tumor necrosis factor-&agr; (TNF&agr;) and interleukin-1 (IL-1) have been recognized as key proinflammatory mediators in the… 
Highly Cited
2001
Highly Cited
2001
Involvement of p38 mitogen-activated protein kinase followed by chemokine expression in crescentic glomerulonephritis.
p38 Mitogen-activated protein kinase (MAPK) is involved in the production and signal transduction of interleukin-1beta (IL-1beta… 
2001
2001
Mechanism for Helicobacter pylori stimulation of interleukin-8 production in a gastric epithelial cell line (MKN 28): roles of mitogen-activated protein kinase and interleukin-1beta.
Highly Cited
2001
Highly Cited
2001
The Role of Tumor Necrosis Factor-α and Interleukin-1β in Ischemia-Reperfusion Injury of the Rat Small Intestine☆
Abstract Background. To determine the role of tumor necrosis factor (TNF) and interleukin (IL)-1 in small-intestinal ischemia… 
Highly Cited
2000
Highly Cited
2000
A new anti-inflammatory compound, FR167653, ameliorates crescentic glomerulonephritis in Wistar-Kyoto rats.
The pathophysiologic effects of FR167653 were investigated in a model of crescentic glomerulonephritis induced by a small dose of… 
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