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FR 167653
Known as:
FR167653
National Institutes of Health
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Related topics
Related topics
5 relations
Broader (5)
Anti-Inflammatory Agents, Non-Steroidal
Growth Inhibitors
Immunosuppressive Agents
Pyrazoles
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Activation of p38 Mitogen-activated Protein Kinase in Spinal Microglia Contributes to Incision-induced Mechanical Allodynia
Y. Wen
,
M. Suter
,
+6 authors
Chia-Chuan Wang
Anesthesiology
2009
Corpus ID: 29813976
Background:Recent studies have implicated the activation of stress-activated mitogen-activated protein kinase (MAPK) p38 in…
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Highly Cited
2007
Highly Cited
2007
Effect of TNF-α inhibition on urinary albumin excretion in experimental diabetic rats
Y. Moriwaki
,
T. Inokuchi
,
+4 authors
Tetsuya Yamamoto
Acta Diabetologica
2007
Corpus ID: 37531515
The objective is to assess the effect of TNF-α inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar…
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Highly Cited
2006
Highly Cited
2006
Opposing effect of p38 MAP kinase and JNK inhibitors on the development of heart failure in the cardiomyopathic hamster.
S. Kyoi
,
H. Otani
,
+7 authors
T. Iwasaka
Cardiovascular Research
2006
Corpus ID: 27671276
Highly Cited
2005
Highly Cited
2005
Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome.
M. Koshikawa
,
M. Mukoyama
,
+9 authors
K. Nakao
Journal of the American Society of Nephrology
2005
Corpus ID: 40556219
Podocytes play an important role in maintaining normal glomerular function and structure, and podocyte injury leads to…
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Highly Cited
2005
Highly Cited
2005
Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia
T. Mizushima
,
K. Obata
,
+5 authors
K. Noguchi
Pain
2005
Corpus ID: 6657349
Highly Cited
2003
Highly Cited
2003
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653.
M. Nishikawa
,
A. Myoui
,
T. Tomita
,
K. Takahi
,
A. Nampei
,
H. Yoshikawa
Arthritis & Rheumatism
2003
Corpus ID: 6470221
OBJECTIVE FR167653 is a potent inhibitor of p38 mitogen-activated protein kinase (MAPK) and inhibits tumor necrosis factor alpha…
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Highly Cited
2001
Highly Cited
2001
FR167653, a p38 mitogen-activated protein kinase inhibitor, prevents Helicobacter pylori-induced gastritis in Mongolian gerbils.
S. Takahashi
,
Y. Keto
,
T. Fujita
,
T. Uchiyama
,
A. Yamamoto
Journal of Pharmacology and Experimental…
2001
Corpus ID: 11077836
FR167653 was discovered as a cytokine production inhibitor, but its target molecule has remained unclear. We examined the effect…
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Highly Cited
2000
Highly Cited
2000
Role of p38 Mitogen-Activated Protein Kinase in Neointimal Hyperplasia After Vascular Injury
N. Ohashi
,
A. Matsumori
,
+6 authors
S. Sasayama
Arteriosclerosis, Thrombosis and Vascular Biology
2000
Corpus ID: 40417621
Abstract—p38 mitogen-activated protein kinase (MAPK) is involved in intracellular signals that regulate a variety of cellular…
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Highly Cited
1999
Highly Cited
1999
Roles of enterobacteria, nitric oxide and neutrophil in pathogenesis of indomethacin-induced small intestinal lesions in rats.
A. Konaka
,
S. Kato
,
A. Tanaka
,
T. Kunikata
,
R. Korolkiewicz
,
K. Takeuchi
Pharmacological Research
1999
Corpus ID: 23047133
Roles of enterobacteria, nitric oxide (NO) and neutrophil in indomethacin-induced small intestinal lesions were examined in rats…
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Highly Cited
1996
Highly Cited
1996
Effect of FR167653, a cytokine suppressive agent, on endotoxin-induced disseminated intravascular coagulation.
N. Yamamoto
,
F. Sakai
,
H. Yamazaki
,
K. Nakahara
,
M. Okuhara
European Journal of Pharmacology
1996
Corpus ID: 4551654
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