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FLRT3 gene

Known as: Fibronectin Leucine Rich Transmembrane Protein 3 Gene, fibronectin leucine rich transmembrane protein 3, FIBRONECTIN-LIKE DOMAIN-CONTAINING LEUCINE-RICH TRANSMEMBRANE PROTEIN 3 
This gene is involved in apoptotic regulation.
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisFLRT3 protein, humanPositive Regulation of Apoptosis

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FLRT3 wt Allele

Papers overview

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2020
2020
Identification of key genes associated with progression and prognosis for lung squamous cell carcinoma
Background Lung squamous cell carcinoma (LUSC) is a major subtype of lung cancer with limited therapeutic options and poor… Expand
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2018
2018
Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression
Dear Editor, The progression of acute myeloid leukemia (AML)—the most severe blood/bone marrow cancer—is determined by the… Expand
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2015
2015
Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.
Fibronectin leucine-rich repeat transmembrane proteins (FLRTs) are cell-adhesion molecules with emerging functions in cortical… Expand
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Highly Cited
2013
Highly Cited
2013
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.
Congenital hypogonadotropic hypogonadism (CHH) and its anosmia-associated form (Kallmann syndrome [KS]) are genetically… Expand
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2009
2009
Unc5B Interacts with FLRT3 and Rnd1 to Modulate Cell Adhesion in Xenopus Embryos
The FLRT family of transmembrane proteins has been implicated in the regulation of FGF signalling, neurite outgrowth, homotypic… Expand
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2009
2009
A Protocadherin-Cadherin-FLRT3 Complex Controls Cell Adhesion and Morphogenesis
BACKGROUND Paraxial protocadherin (PAPC) and fibronectin leucine-rich domain transmembrane protein-3 (FLRT3) are induced by… Expand
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2008
2008
Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation.
During early mouse development, the anterior visceral endoderm (AVE) secretes inhibitor and activator signals that are essential… Expand
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2008
2008
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III… Expand
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2004
2004
FLRT3, a cell surface molecule containing LRR repeats and a FNIII domain, promotes neurite outgrowth.
The mature peripheral nervous system has the ability to survive and to regenerate its axons following axonal injury. After nerve… Expand
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Highly Cited
1999
Highly Cited
1999
Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.
FLRT1, FLRT2, and FLRT3 comprise a novel gene family isolated in a screen for extracellular matrix proteins expressed in muscle… Expand
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