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FKBP5 gene

Known as: FK506 Binding Protein 5 Gene, FKBP5, FK506-BINDING PROTEIN, 51-KD 
This gene plays a role in protein folding.
National Institutes of Health

Related topics

Related topics

10 relations
FKBP1A geneFKBP1B geneFKBP2 geneFKBP3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Methylation of the FKBP5 gene in association with FKBP5 genotypes, childhood maltreatment and depression
DNA methylation of the FKBP5 gene is assumed to alter FKBP5 expression and hence the synthesis of the FK506 binding protein 51, a… 
Highly Cited
2011
Highly Cited
2011
Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90
ABSTRACT Some hypervirulent strains of Clostridium difficile produce the binary actin-ADP-ribosylating toxin C. difficile… 
Highly Cited
2008
Highly Cited
2008
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
Mood and anxiety disorders are considered stress‐related diseases characterized by an impaired function of mineralocorticoid and… 
Highly Cited
2007
Highly Cited
2007
Essential Role for Co-chaperone Fkbp52 but Not Fkbp51 in Androgen Receptor-mediated Signaling and Physiology*
Fkbp52 and Fkbp51 are tetratricopeptide repeat proteins found in steroid receptor complexes, and Fkbp51 is an androgen receptor… 
Highly Cited
2005
Highly Cited
2005
Differential control of glucocorticoid receptor hormone-binding function by tetratricopeptide repeat (TPR) proteins and the immunosuppressive ligand FK506.
Many laboratories have documented the existence of tetratricopeptide repeat (TPR) proteins (also known as immunophilins) in… 
Highly Cited
2005
Highly Cited
2005
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.
PURPOSE Androgen ablation continues to be the most effective therapy for metastatic prostate cancer, although the biologically… 
Highly Cited
2004
Highly Cited
2004
Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids
Abstract Expression of FKBP51, a large molecular weight immunophilin, is strongly enhanced by glucocorticoids, progestins, and… 
Review
2003
Review
2003
Immunophilin chaperones in steroid receptor signalling.
The immunophilin cochaperones, cyclophilin 40 (CyP40), FKBP51 and FKBP52 and PP5, a serine/threonine protein phosphatase, have… 
Highly Cited
2001
Highly Cited
2001
Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40.
Large peptidyl-prolyl cis/trans isomerases (PPIases) are important components of the Hsp90 chaperone complex. In mammalian cells… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor
A cDNA for human FKBP51 has been cloned and sequenced, and protein products have been expressed in both in vitro and bacterial… 
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