FH wt Allele

Known as: MCUL1, Fumarate Hydratase wt Allele, LRCC 
Human FH wild-type allele is located in the vicinity of 1q42.1 and is approximately 22 kb in length. This allele, which encodes fumarate hydratase… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
02419942017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) is caused by germline mutations in the fumarate hydratase (FH… (More)
Is this relevant?
2013
2013
OBJECTIVE The standard therapy for advanced hepatocellular carcinoma (HCC) is sorafenib, with most patients experiencing disease… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2012
2012
Label-retaining cells (LRCs) have been proposed to represent adult tissue stem cells. LRCs are hypothesized to result from either… (More)
Is this relevant?
2012
2012
The role of energy deregulation and altered/adapted metabolism in tumor cells is an increasingly important issue in understanding… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Germline mutations in the FH gene encoding the Krebs cycle enzyme fumarate hydratase predispose to hereditary leiomyomatosis and… (More)
Is this relevant?
2011
2011
BACKGROUND Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant disorder predisposing humans to… (More)
Is this relevant?
2009
2009
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a tumor predisposition syndrome with cutaneous and uterine… (More)
  • figure 1
Is this relevant?
2007
2007
Germline mutations in nuclear genes encoding mitochondrial enzymes fumarate hydratase (FH) and succinate dehydrogenase (subunits… (More)
Is this relevant?
2005
2005
Multiple cutaneous and uterine leiomyomata syndrome (MCL) is an autosomal dominant disease characterized by the presence of… (More)
  • table 1
Is this relevant?
2001
2001
Dominant transmission of multiple uterine and cutaneous smooth-muscle tumors is seen in the disorder multiple leiomyomatosis (ML… (More)
Is this relevant?