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FGR gene

Known as: SRC2 ONCOGENE, FORMERLY, c-fgr, FGR ONCOGENE 
Human Oncogene FGR is a mutated variant of FGR Gene (SRC Family), which encodes 529-aa 60-kDa p55-FGR, a protein tyrosine kinase that may bind PTPNS1… 
National Institutes of Health

Related topics

Related topics

12 relations
1p36.2-p36.1Cell Differentiation processCell ProliferationFGR protein, human

Papers overview

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Highly Cited
2006
Highly Cited
2006
Identification of newborns with Fetal Growth Restriction (FGR) in weight and/or length based on constitutional growth potential
This study was carried out to build statistical models for defining FGR (Fetal Growth Restriction) in weight and/or length after… 
2006
2006
Genetic expression profiles and chromosomal alterations in sporadic breast cancer in Mexican women.
Highly Cited
1999
Highly Cited
1999
Novel association of the src family kinases, hck and c-fgr, with CCR3 receptor stimulation: A possible mechanism for eotaxin-induced human eosinophil chemotaxis.
The chemokine eotaxin is a potent and relatively eosinophil-specific chemoattractant implicated in the cell migration to… 
Highly Cited
1996
Highly Cited
1996
Activation of SRC family kinases in human neutrophils. Evidence that p58c‐frg and p53/56lyn redistributed to a Triton X‐100‐insoluble cytoskeletal fraction, also enriched in the caveolar protein…
Highly Cited
1996
Highly Cited
1996
Lyn and Fgr Protein-tyrosine Kinases Prevent Apoptosis during Retinoic Acid-induced Granulocytic Differentiation of HL-60 Cells (*)
The human promyelocytic leukemia cell line HL-60 can be induced to differentiate toward neutrophils and subsequently die via… 
1996
1996
A comparative analysis of the photosensitized inhibition of growth-factor regulated protein kinases by hypericin-derivatives.
The photodynamic inhibitory effect of hypericin and a number of hypericin-derivatives were investigated in vitro using numerous… 
1993
1993
Isolation and identification of two proto-oncogene products related to c-fgr and fyn in a tyrosine-protein-kinase fraction of rat spleen.
TPK-III, a tyrosine-protein-kinase fraction previously isolated from rat spleen [Brunati, A. M. & Pinna, L. A. (1988) Eur. J… 
Highly Cited
1991
Highly Cited
1991
Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src.
Phosphorylation of the carboxyl terminus of pp60c-src, the product of the c-src protooncogene, at Tyr-527 suppresses its tyrosine… 
Highly Cited
1989
Highly Cited
1989
Tissue-specific expression and developmental regulation of the human fgr proto-oncogene
In this study, we show that c-fgr proto-oncogene expression is limited to normal peripheral blood granulocytes, monocytes, and… 
Highly Cited
1986
Highly Cited
1986
Structure, expression, and chromosomal location of the human c-fgr gene
The nucleotide sequence of seven exons of the human c-fgr gene, a cellular homolog of the oncogene of Gardner-Rasheed feline… 
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