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FCGR2B wt Allele

Known as: Fc Fragment of IgG, Low Affinity IIB, Receptor for Gene, CD32B, Fc Fragment of IgG, Low Affinity IIB, Receptor for (CD32) 
Human FCGR2B wild-type allele is located within 1q23 and is approximately 15 kb in length. This allele, which encodes low affinity immunoglobulin… 
National Institutes of Health

Related topics

Related topics

16 relations
1q23B Cell Receptor Signaling PathwayB-Cell ActivationCD32 Antigens

Broader (1)

FCGR2B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB
Fc γ receptors (FcγR) are involved in multiple aspects of immune cell regulation, are central to the success of mAb therapeutics… 
2017
2017
CD32b expression is down-regulated on double-negative memory B cells in patients with Hashimoto's thyroiditis
2016
2016
Immunohistochemical detection of CD14 and combined assessment with CD32B and CD68 for wound age estimation.
2016
2016
OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers
Background MGD010, a bi-specific Dual-Affinity Re-Targeting, or DART®, molecule, inhibits activated B-cells by delivering a… 
2014
2014
Defunctioning Polymorphism in the Immunoglobulin G Inhibitory Receptor (Fc&ggr;RIIB-T/T232) Does not Impact on Kidney Transplant or Recipient Survival
Background There is an increasing appreciation of the deleterious effects of antibody and B cells on acute and chronic transplant… 
2010
2010
Effect of immunoglobulin G (IgG) interchain disulfide bond cleavage on efficacy of intravenous immunoglobulin for immune thrombocytopenic purpura (ITP)
Intravenous immunoglobulin (IVIG) has been used widely to treat immune thrombocytopenic purpura (ITP), but the mechanisms of its… 
Highly Cited
2007
Highly Cited
2007
Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus.
FcgammaRIIb (CD32B, Online Mendelian Inheritance in Man 604590), an IgG FcR with a tyrosine-based inhibitory motif, plays a… 
2006
2006
CD 32 B , the human inhibitory Fc-receptor IIB , as a target for monoclonal antibody therapy of B-cell lymphoma
Human CD32B (Fc RIIB), the low-affinity inhibitory receptor for IgG, is the predominant Fc receptor (FcR) present on B cells… 
2005
2005
Intravenous immunoglobulin does not increase FcgammaRIIB expression on monocytes/macrophages during acute Kawasaki disease.
OBJECTIVES Intravenous immunoglobulin (IVIG) therapy has been reported to be effective for reducing the incidence of coronary… 
Review
2004
Review
2004
Functional regulation of human neutrophil Fc gamma receptors.
Interaction between Fc receptors expressed on phagocytic cells and antibodies play a critical role in innate immune response… 
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