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FCGR2B wt Allele

Known as: Fc Fragment of IgG, Low Affinity IIB, Receptor for Gene, CD32B, Fc Fragment of IgG, Low Affinity IIB, Receptor for (CD32) 
Human FCGR2B wild-type allele is located within 1q23 and is approximately 15 kb in length. This allele, which encodes low affinity immunoglobulin… 
National Institutes of Health

Related topics

Related topics

16 relations
1q23B Cell Receptor Signaling PathwayB-Cell ActivationCD32 Antigens

Broader (1)

FCGR2B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Decreased expression of FcγRII in active Graves' disease patients
Graves' disease (GD) is a common autoimmune disease characterized by genetic and environmental factors. Fcγ receptors (FcγRs) are… 
2019
2019
Combined manual and automated immunophenotypisation identified disease-specific peripheral blood immune subpopulations in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis.
OBJECTIVES Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are associated with abnormal… 
2018
2018
Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB
Fc γ receptors (FcγR) are involved in multiple aspects of immune cell regulation, are central to the success of mAb therapeutics… 
2017
2017
CD32b expression is down-regulated on double-negative memory B cells in patients with Hashimoto's thyroiditis
2017
2017
Abstract OT1-02-07: SOPHIA: A phase 3, randomized study of margetuximab plus chemotherapy vs trastuzumab plus chemotherapy in the treatment of patients with HER2+ metastatic breast cancer
Background: Despite significant advances in targeted therapy, HER2+ metastatic breast cancer (MBC) remains incurable. Ideal… 
2014
2014
Defunctioning Polymorphism in the Immunoglobulin G Inhibitory Receptor (Fc&ggr;RIIB-T/T232) Does not Impact on Kidney Transplant or Recipient Survival
Background There is an increasing appreciation of the deleterious effects of antibody and B cells on acute and chronic transplant… 
2014
2014
De‐functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival
Renal transplantation represents the optimal treatment for most patients with end-stage renal failure. Although there has been an… 
2010
2010
Effect of immunoglobulin G (IgG) interchain disulfide bond cleavage on efficacy of intravenous immunoglobulin for immune thrombocytopenic purpura (ITP)
Intravenous immunoglobulin (IVIG) has been used widely to treat immune thrombocytopenic purpura (ITP), but the mechanisms of its… 
2006
2006
CD 32 B , the human inhibitory Fc-receptor IIB , as a target for monoclonal antibody therapy of B-cell lymphoma
Human CD32B (Fc RIIB), the low-affinity inhibitory receptor for IgG, is the predominant Fc receptor (FcR) present on B cells… 
2005
2005
Intravenous immunoglobulin does not increase FcgammaRIIB expression on monocytes/macrophages during acute Kawasaki disease.
OBJECTIVES Intravenous immunoglobulin (IVIG) therapy has been reported to be effective for reducing the incidence of coronary… 
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