FBXO5 gene

Known as: EMI1, XENOPUS, HOMOLOG OF, FBX5, FBXO5 
This gene plays a role in the modulation of cell cycle progression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
024620002018

Papers overview

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2015
2015
Passage through mitosis is driven by precisely-timed changes in transcriptional regulation and protein degradation. However, the… (More)
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2009
2009
Several regulatory proteins control cell cycle progression. These include Emi1, an anaphase-promoting complex (APC) inhibitor… (More)
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Highly Cited
2008
Highly Cited
2008
In vitro, the anaphase-promoting complex (APC) E3 ligase functions with E2 ubiquitin-conjugating enzymes of the E2-C and Ubc4/5… (More)
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Highly Cited
2007
Highly Cited
2007
Emi1 (early mitotic inhibitor) inhibits APC/C (anaphase-promoting complex/cyclosome) activity during S and G2 phases, and is… (More)
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Highly Cited
2006
Highly Cited
2006
Proliferating cells have a higher metabolic rate than quiescent cells. To investigate the role of metabolism in cell cycle… (More)
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2006
2006
The anaphase promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that controls the cell cycle by directing the… (More)
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Highly Cited
2004
Highly Cited
2004
Progression through mitosis requires activation of cyclin B/Cdk1 and its downstream targets, including Polo-like kinase and the… (More)
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2004
2004
Oocytes of most vertebrates arrest at metaphase of the second meiosis (meta-II) to await fertilization, thus preventing… (More)
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Highly Cited
2003
Highly Cited
2003
Progression through mitosis occurs because cyclin B/Cdc2 activation induces the anaphase promoting complex (APC) to cause cyclin… (More)
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Highly Cited
2001
Highly Cited
2001
The anaphase-promoting complex/cyclosome (APC) ubiquitin ligase is activated by Cdc20 and Cdh1 and inhibited by Mad2 and the… (More)
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