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FBXO32 gene

Known as: MUSCLE ATROPHY F-BOX, MAFbx, FBXO32 
This gene plays a role in protein ubiquitination and degradation.
National Institutes of Health

Related topics

Related topics

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F-Box Only Protein 32

Papers overview

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2019
2019
Atrogin-1/MAFbx mRNA expression is regulated by histone deacetylase 1 in rat soleus muscle under hindlimb unloading
It is known that MuRF-1 and atrogin-1/MAFbx mRNA expression is increased in rat soleus muscle under unloading conditions. We… 
2016
2016
Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
Cancer cachexia is a multifactorial syndrome affecting the skeletal muscle. Previous clinical trials showed that treatment with… 
Highly Cited
2014
Highly Cited
2014
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)
The Polycomb group (PcG) proteins regulate stem cell differentiation via the repression of gene transcription, and their… 
2010
2010
Characterisation and differential regulation of MAFbx/Atrogin-1 alpha and beta transcripts in skeletal muscle of Atlantic salmon (Salmo salar).
Highly Cited
2009
Highly Cited
2009
Ghrelin inhibits skeletal muscle protein breakdown in rats with thermal injury through normalizing elevated expression of E3 ubiquitin ligases MuRF1 and MAFbx.
We previously determined that ghrelin synthesis was downregulated after burn injury and that exogenous ghrelin retained its… 
2008
2008
Effects of nandrolone on denervation atrophy depend upon time after nerve transection
Anabolic steroids prevent disuse atrophy and reverse atrophy caused by glucocorticoids. To determine whether these beneficial… 
2008
2008
Decreased muscle atrophy F‐box (MAFbx) expression in regenerating muscle after muscle‐damaging exercise
A muscle‐specific ubiquitin ligase, Muscle Atrophy F‐box (MAFbx), is known to mediate the degradation of muscle‐specific… 
2008
2008
Effect of botulinum toxin A‐induced paralysis and exercise training on mechanosensing and signalling gene expression in juvenile rat gastrocnemius muscle
Intramuscular injections of the paralytic botulinum neurotoxin A (Btx) and physical exercise are used in the treatment of chronic… 
Highly Cited
2005
Highly Cited
2005
Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle.
Chronic arthritis is a catabolic state associated with an inhibition of the IGF system and a decrease in body weight. Cachexia… 
Highly Cited
2003
Highly Cited
2003
Induction of MafBx and Murf ubiquitin ligase mRNAs in rat skeletal muscle after LPS injection
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