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FANCONI ANEMIA, COMPLEMENTATION GROUP J

Known as: FANCJ 
Fanconi anemia caused by mutations in the BRIP1 gene, encoding Fanconi anemia group J protein.
National Institutes of Health

Related topics

Related topics

7 relations
AnemiaBACH1 geneBRIP1 wt AlleleBRIP1, ARG798TER
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Broader (1)

Fanconi Anemia

Papers overview

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Highly Cited
2014
Highly Cited
2014
Detection of G-quadruplex DNA in mammalian cells
It has been proposed that guanine-rich DNA forms four-stranded structures in vivo called G-quadruplexes or G4 DNA. G4 DNA has… Expand
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Highly Cited
2013
Highly Cited
2013
Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability*
Background: The Fe-S helicase FANCJ implicated in Fanconi anemia plays important roles in DNA replication and repair. Results… Expand
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Review
2011
Review
2011
Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1.
It is clear that FANCJ, also known as BACH1 or BRIP1, is an essential tumor suppressor gene based on the identification of… Expand
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Highly Cited
2011
Highly Cited
2011
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome
Bloom's syndrome (BS) and Fanconi anemia (FA) are autosomal recessive disorders characterized by cancer and chromosomal… Expand
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Highly Cited
2009
Highly Cited
2009
Structure, function and evolution of the XPD family of iron-sulfur-containing 5'-->3' DNA helicases.
  • M. White
  • Biochemical Society transactions
  • 2009
    • Corpus ID: 36966982
The XPD (xeroderma pigmentosum complementation group D) helicase family comprises a number of superfamily 2 DNA helicases with… Expand
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Highly Cited
2008
Highly Cited
2008
FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability
ABSTRACT FANCJ mutations are associated with breast cancer and genetically linked to the bone marrow disease Fanconi anemia (FA… Expand
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Review
2008
Review
2008
Welcome the Family of FANCJ-like Helicases to the Block of Genome Stability Maintenance Proteins
Abstract.The FANCJ family of DNA helicases is emerging as an important group of proteins for the prevention of human disease… Expand
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Highly Cited
2008
Highly Cited
2008
Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families
Recent reports have shown that mutations in the FANCJ/BRIP1 and FANCN/PALB2 Fanconi Anemia (FA) genes confer a moderate breast… Expand
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Highly Cited
2005
Highly Cited
2005
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
The protein predicted to be defective in individuals with Fanconi anemia complementation group J (FA-J), FANCJ, is a missing… Expand
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Highly Cited
2005
Highly Cited
2005
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
We showed in this study that cells deficient of the BRCA1-associated BACH1 helicase, also known as BRIP1, failed to elicit… Expand
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