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BACH1 gene

Known as: BTB AND CNC HOMOLOGY 1, BTB domain and CNC homolog 1, BACH1 
National Institutes of Health

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FANCONI ANEMIA, COMPLEMENTATION GROUP J

Papers overview

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Highly Cited
2019
Highly Cited
2019
BTB and CNC homology 1 (Bach1) promotes human ovarian cancer cell metastasis by HMGA2-mediated epithelial-mesenchymal transition.
Review
2018
Review
2018
Bach1: Function, Regulation, and Involvement in Disease
The transcription factor BTB and CNC homology 1 (Bach1) is widely expressed in most mammalian tissues and functions primarily as… 
Highly Cited
2018
Highly Cited
2018
miR‐142‐3p as tumor suppressor miRNA in the regulation of tumorigenicity, invasion and migration of human breast cancer by targeting Bach‐1 expression
Breast cancer is the most common type of cancer among women, and despite improved treatments, it remains a major challenge… 
2018
2018
MicroRNA-98-5p ameliorates oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by inhibiting Bach1 and promoting Nrf2/ARE signaling.
Highly Cited
2017
Highly Cited
2017
Hepatocyte‐specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up‐regulation of Bach1, an Nrf2 repressor
Sirtuin (Sirt)6 has been implicated in negative regulation of inflammation and lipid metabolism, although its function in the… 
Highly Cited
2016
Highly Cited
2016
Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation
The transcription factor BTB and CNC homology 1 (Bach1) regulates genes involved in the oxidative stress response and cell-cycle… 
2013
2013
A Novel CXCR3-B Chemokine Receptor-induced Growth-inhibitory Signal in Cancer Cells Is Mediated through the Regulation of Bach-1 Protein and Nrf2 Protein Nuclear Translocation*
Background: The chemokine receptor CXCR3-B initiates inhibitory signals. Results: CXCR3-B-mediated signal induced apoptosis and… 
Highly Cited
2012
Highly Cited
2012
Identification of a novel role of ESAT‐6‐dependent miR‐155 induction during infection of macrophages withMycobacterium tuberculosis
Mycobacterium tuberculosis (M.tb.) replicates in host macrophages to cause tuberculosis. We have investigated the role of miRNAs… 
Highly Cited
2010
Highly Cited
2010
Expression of heme oxygenase‐1 in human leukemic cells and its regulation by transcriptional repressor Bach1
Heme oxygenase (HO)‐1 has anti‐oxidative, anti‐inflammatory, and anti‐apoptotic activities. However, little is known about the… 
Highly Cited
2004
Highly Cited
2004
Role of Bach-1 in Regulation of Heme Oxygenase-1 in Human Liver Cells
Heme oxygenase-1 is an antioxidant defense enzyme that converts heme to biliverdin, iron, and carbon monoxide. Bach-1 is a bZip… 
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