FANCONI ANEMIA, COMPLEMENTATION GROUP D2

Known as: FANCONI ANEMIA, COMPLEMENTATION GROUP D, FAD2, FANCD2 
Fanconi anemia caused by mutations of the FANCD2 gene. This gene is involved in the repair of DNA double-strand breaks, both by homologous… (More)
National Institutes of Health

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29 relations
Abnormal renal morphologyAnemiaAnemic pallorAutosomal recessive inheritance
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA.
The transition from ductal carcinoma in situ to invasive ductal carcinoma is a key event in breast cancer progression that is… (More)
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Highly Cited
2010
Highly Cited
2010
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.
Fanconi anemia (FA) is a complex cancer susceptibility disorder associated with DNA repair defects and infertility, yet the… (More)
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Highly Cited
2009
Highly Cited
2009
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.
Fanconi anemia (FA) is a human genetic disease characterized by chromosome instability, cancer predisposition, and cellular… (More)
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Highly Cited
2005
Highly Cited
2005
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.
Fanconi anemia (FA) is a recessive disorder characterized by congenital abnormalities, progressive bone-marrow failure, and… (More)
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Highly Cited
2004
Highly Cited
2004
Membrane-bound fatty acid desaturases are inserted co-translationally into the ER and contain different ER retrieval motifs at their carboxy termini.
Fatty acid desaturases (FADs) play a prominent role in plant lipid metabolism and are located in various subcellular compartments… (More)
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Highly Cited
2002
Highly Cited
2002
hpRNA-mediated targeting of the Arabidopsis FAD2 gene gives highly efficient and stable silencing.
The endogenous Delta 12-desaturase gene (FAD2) in Arabidopsis was targeted for silencing using seed-specific cosuppression (CS… (More)
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2001
2001
Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells.
OBJECTIVE Fanconi anemia (FA) is a human autosomal-recessive cancer susceptibility disorder characterized by multiple congenital… (More)
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Highly Cited
2000
Highly Cited
2000
The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG.
Fanconi anemia (FA) is a chromosomal instability syndrome associated with a strong predisposition to cancer, particularly acute… (More)
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Highly Cited
1998
Highly Cited
1998
The Fanconi anaemia group G gene FANCG is identical with XRCC9
Fanconi anemia (FA) is an autosomal recessive disease with diverse clinical symptoms including developmental anomalies, bone… (More)
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Highly Cited
1994
Highly Cited
1994
Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis.
The polyunsaturated fatty acids linoleate and alpha-linolenate are important membrane components and are the essential fatty… (More)
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