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FANCM gene

Known as: Fanconi anemia complementation group M, FANCM, FANCONI ANEMIA-ASSOCIATED POLYPEPTIDE, 250-KD 
This gene plays a role in transcriptional regulation and ubiquitination.
National Institutes of Health

Papers overview

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2014
2014
Genetic recombination is important for generating diversity and to ensure faithful segregation of chromosomes at meiosis. However… Expand
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Highly Cited
2014
Highly Cited
2014
Inherited predisposition to breast cancer is known to be caused by loss-of-function mutations in BRCA1, BRCA2, PALB2, CHEK2, and… Expand
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Highly Cited
2012
Highly Cited
2012
The number of meiotic crossovers (COs) is tightly regulated within a narrow range, despite a large excess of molecular precursors… Expand
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Highly Cited
2010
Highly Cited
2010
FANCM is a Fanconi anemia nuclear core complex protein required for the functional integrity of the FANC-BRCA pathway of DNA… Expand
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Highly Cited
2009
Highly Cited
2009
The Fanconi anemia (FA) core complex member FANCM remodels synthetic replication forks and recombination intermediates. Thus far… Expand
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Highly Cited
2009
Highly Cited
2009
Fanconi Anemia (FA) and Bloom's Syndrome (BS) are genetic disorders characterized by overlapping phenotypes, including aberrant… Expand
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Highly Cited
2008
Highly Cited
2008
Fanconi anemia (FA) is a genetically heterogeneous chromosome instability syndrome associated with congenital abnormalities, bone… Expand
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Highly Cited
2008
Highly Cited
2008
The Fanconi anemia (FA) pathway is implicated in DNA repair and cancer predisposition. Central to this pathway is the FA core… Expand
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Highly Cited
2008
Highly Cited
2008
Fanconi anemia (FA) is a genetic disease characterized by congenital abnormalities, bone marrow failure, and cancer… Expand
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Highly Cited
2007
Highly Cited
2007
The Fanconi anemia (FA) core complex plays a crucial role in a DNA damage response network with BRCA1 and BRCA2. How this complex… Expand
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