Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion.

@article{Ede2011BuddingYM,
  title={Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion.},
  author={Christopher Ede and Christian J Rudolph and Sabrina Lehmann and Kirsten Anke Sch{\"u}rer and Wilfried Kramer},
  journal={DNA repair},
  year={2011},
  volume={10 1},
  pages={
          45-55
        }
}
Stalling of replication forks at lesions is a serious threat to genomic integrity and cell viability. Cells have developed a variety of pathways that allow continuation of synthesis, including translesion synthesis, postreplication repair and homologous recombination. We have devised a sensitive genetic system for detection of sister chromatid interactions in Saccharomyces cerevisiae. A 266bp sequence duplication in the KanMX4 module was generated and reversions were scored via G418 resistant… CONTINUE READING
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