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FANCD2 gene

Known as: FAD, Fanconi anemia complementation group D2, FANCD2 
This gene is involved in the regulation of meiosis, DNA repair and the cell cycle.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlDNA RepairDNA stabilityFANCONI ANEMIA, COMPLEMENTATION GROUP D2

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FANCD2 wt Allele

Papers overview

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2018
2018
Dysfunctional DNA repair pathway via defective FANCD2 gene engenders multifarious exomic and transcriptomic effects in Fanconi anemia
Fanconi anemia (FA) affects only one in 130,000 births, but has severe and diverse clinical consequences. It has been theorized… 
2017
2017
Cytoprotective Effects and Mechanisms of Δ-17 Fatty Acid Desaturase in Injured Human Umbilical Vein Endothelial Cells (HUVECs)
Background The beneficial effect of Δ-17 FAD is poorly understood. The aim of this study was to investigate the protective… 
2014
2014
Fancd2 Is Required for Nuclear Retention of Foxo3a in Hematopoietic Stem Cell Maintenance*
Background: Maintenance of HSCs is challenged by DNA damage and oxidative stress. Results: Fancd2 deficiency promoted cytoplasmic… 
2014
2014
Effects of Bisphenol A and Fadrozole Exposures on cyp19a1 Expression in the Murray Rainbowfish, Melanotaenia fluviatilis
Several endocrine-disrupting chemicals (EDCs) have been attributed to the alteration of reproduction in fish through disrupting… 
2012
2012
Microbial urate catabolism: characterization of HpyO, a non-homologous isofunctional isoform of the flavoprotein urate hydroxylase HpxO.
In aerobic cells, urate is oxidized to 5-hydroxyisourate by two distinct enzymes: a coenzyme-independent urate oxidase (EC 1.7.3… 
2010
2010
Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation.
Human β-defensins (hBDs) are small, cationic antimicrobial peptides, secreted by mucosal epithelial cells that regulate adaptive… 
2007
2007
A novel Leu153Ser mutation of the Fanconi anemia FANCD2 gene is associated with severe chemotherapy toxicity in a pediatric T-cell acute lymphoblastic leukemia
Fanconi anemia (FA) is an autosomal recessive disease characterized by pancitopenia, congenital malformations, predisposition to… 
2005
2005
The Caenorhabditis elegans FancD2 ortholog is required for survival following DNA damage.
2005
2005
Potential candidate stratotypes for the FAD levels Lejopyge laevigata and Agnostotes orientalis
Highly Cited
2003
Highly Cited
2003
siRNA depletion of BRCA1, but not BRCA2, causes increased genome instability in Fanconi anemia cells.
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