FAM20C gene

Levels of serum phosphate are controlled by the peptide hormone FGF23, secreted from bone osteocytes. Elevated levels of… (More)

BACKGROUND Hypophosphatemia and increased serum fibroblast growth factor 23 (FGF23) levels have been reported in young brothers… (More)

BACKGROUND FAM20C is a kinase that phosphorylates secretory proteins. Previous studies have shown that FAM20C plays an essential… (More)

Raine syndrome is an autosomal recessive disorder characterized by generalized osteosclerosis with periosteal bone formation and… (More)

Raine syndrome is an autosomal recessive disorder caused by mutations in the FAM20C gene that is characterized by generalized… (More)

Previously, we showed that Sox2-Cre;Fam20C(fl/fl) mice in which Fam20C was ubiquitously inactivated had severe defects in dentin… (More)

FAM20C, also known as Golgi casein kinase (G-CK), is proposed to be the archetype for a family of secreted kinases that… (More)

Raine syndrome is caused by mutations in FAM20C, which had been reported to encode a secreted component of bone and teeth. We… (More)

Raine syndrome is an autosomal recessive disorder caused by mutations in the FAM20C gene. FAM20C codes for the human homolog of… (More)

The generation and homeostasis of bone tissue throughout development and maturity is controlled by the carefully balanced… (More)