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FAM20C gene

Known as: IMAGE:4942737, FAMILY WITH SEQUENCE SIMILARITY 20, MEMBER C, DKFZp547D065 
National Institutes of Health

Related topics

Related topics

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FAM20B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density…
OBJECTIVE PCSK9 (proprotein convertase subtilisin-kexin 9) enhances the degradation of the LDLR (low-density lipoprotein receptor… 
2016
2016
FAM20A binds to and regulates FAM20C localization
Mutations in the Family with sequence similarity (FAM) 20 gene family are associated with mineralized tissue phenotypes in humans… 
2016
2016
Immunohistochemical analysis of dentin matrix protein 1 (Dmp1) phosphorylation by Fam20C in bone: implications for the induction of biomineralization
Dmp1 is an acidic phosphoprotein that is specifically expressed in osteocytes. During the secretory process, the full-length… 
2013
2013
The Specific Role of FAM20C in Amelogenesis
Previously, we showed that Sox2-Cre;Fam20Cfl/fl mice in which Fam20C was ubiquitously inactivated had severe defects in dentin… 
Highly Cited
2012
Highly Cited
2012
Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice
Family with sequence similarity 20,-member C (FAM20C) is highly expressed in the mineralized tissues of mammals. Genetic studies… 
Highly Cited
2012
Highly Cited
2012
The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins
Raine syndrome is caused by mutations in FAM20C, which had been reported to encode a secreted component of bone and teeth. We… 
Highly Cited
2011
Highly Cited
2011
Osteosclerotic bone dysplasia in siblings with a Fam20C mutation
Fradin M, Stoetzel C, Muller J, Koob M, Christmann D, Debry C, Kohler M, Isnard M, Astruc D, Desprez P, Zorres C, Flori E… 
Highly Cited
2010
Highly Cited
2010
Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse
Mutations in FAM20C were recently identified as the cause of lethal osteosclerotic bone dysplasia, which highlighted the… 
Highly Cited
2007
Highly Cited
2007
Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine syndrome), highlighting a crucial molecule in bone development.
The generation and homeostasis of bone tissue throughout development and maturity is controlled by the carefully balanced… 
Highly Cited
2007
Highly Cited
2007
Dentin Matrix Protein 4, a Novel Secretory Calcium-binding Protein That Modulates Odontoblast Differentiation*
Formation of calcified tissues is a well regulated process. In dentin, the odontoblasts synthesize several biomolecules that… 
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