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F8 gene

Known as: FACTOR VIII, DXS1253E, Factor VIIIF8B 
This gene plays an important role in blood coagulation.
National Institutes of Health

Related topics

Related topics

10 relations
Blood coagulationCalcium BindingFactor VIIIFactor VIII measurement

Narrower (1)

F8 wt Allele

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors.
The substantial variability in pharmacokinetic parameters in hemophilia patients A poses a challenge for optimal treatment with… 
Highly Cited
2008
Highly Cited
2008
One‐stage and chromogenic FVIII:C assay discrepancy in mild haemophilia A and the relationship with the mutation and bleeding phenotype
Summary.  The discrepancy of the levels of factor VIII activity (FVIII:C) by different assays in some mild and moderate… 
1995
1995
Regulation of 5-aminolevulinic acid synthesis in Rhodobacter sphaeroides 2.4.1: the genetic basis of mutant H-5 auxotrophy
Rhodobacter sphaeroides H-5 was isolated as a 5-aminolevulinic acid (ALA) auxotroph following treatment of wild-type cells with N… 
1995
1995
A Cryptosporidium parvum genomic region encoding hemolytic activity
Successful parasitization by Cryptosporidium parvum requires multiple disruptions in both host and protozoan cell membranes as… 
Review
1993
Review
1993
Spectrum of mutations in CRM-positive and CRM-reduced hemophilia A.
Hemophilia A is due to the functional deficiency of factor VII (FVIII, gene locus F8C). Although half the patients have no… 
1989
1989
Toward a physical map of the Xq28 region in man: linking color vision, G6PD, and coagulation factor VIII genes to an X-Y homology region.
1988
1988
Cloning of hemA from Rhizobium sp. NGR234 and symbiotic phenotype of a gene-directed mutant in diverse legume genera
SummaryThe hemA gene which encodes δ-aminolaevulinic acid synthase (ALAS), was cloned and characterized from the broad host-range… 
Highly Cited
1987
Highly Cited
1987
Structure of the Bradyrhizobium japonicum gene hemA encoding 5-aminolevulinic acid synthase.
1987
1987
Recombination between the factor VIII gene and the DXS52 locus gives the most probable genetic order as centromere-fra(X)-DXS15-DXS52-F8C-telomere.
The linkage relationship between the factor VIII gene (F8C) and the DXS52 locus was examined in 8 families. Two recombinations… 
1986
1986
Physical mapping of the factor VIII gene proximal to two polymorphic DNA probes in human chromosome band Xq28: implications for factor VIII gene segregation analysis.
Genomic DNA segments for the coagulation factor VIIIc gene (F8C), which exhibits only limited restriction length polymorphism… 
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