F15063
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
RationaleThere is increasing interest in antipsychotics intended to manage positive symptoms via D2 receptor blockade and improve…
Interaction at dopamine D4 receptors may improve cognitive function, which is highly impaired in individuals with schizophrenia…
The D2/D3 receptor antagonist, D4 receptor partial agonist, and high efficacy 5‐HT1A receptor agonist F15063 was shown to be…
Combining 5‐HT1A receptor activation with dopamine D2/D3 receptor blockade should improve negative symptoms and cognitive…
F15063 is a high affinity D2/D3 antagonist, D4 partial agonist, and high efficacy 5‐HT1A agonist, with little affinity (40‐fold…
F15063 (N-[(2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl]-3-(cyclopent-1-enyl)-benzylamine fumarate salt) is a novel…