F14512

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2017
02420082017

Papers overview

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2014
2014
The poor prognosis of children with high-grade glioma (HGG) and high-risk neuroblastoma, despite multidisciplinary therapeutic… (More)
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2014
2014
BACKGROUND Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide. The treatment of advanced… (More)
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2013
2013
Chemotherapy remains mainly used for the treatment of acute myeloid leukemia (AML). However, in the past 3 decades limited… (More)
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2011
2011
F14512 is a novel etoposide derivative that contains a spermine in place of the C4 glycosidic moiety. The drug was designed to… (More)
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2011
2011
The polyamines transport system (PTS) is usually enhanced in cancer cells and can be exploited to deliver anticancer drugs. The… (More)
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2011
2011
F14512 is a novel anti-tumor molecule based on an epipodophyllotoxin core coupled to a cancer-cell vectoring spermine moiety… (More)
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2011
2011
F14512, an epipodophyllotoxin derivative equipped with a spermine moiety, is selectively taken up by the polyamine transport… (More)
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2010
2010
The polyamine transport system (PTS), hyperactive in cancer cells, can constitute a gate to deliver F14512, a novel spermine… (More)
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2009
2009
We have exploited the polyamine transport system (PTS) to deliver selectively a spermine-drug conjugate, F14512 to cancer cells… (More)
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2008
2008
The polyamine transport system (PTS) is an energy-dependent machinery frequently overactivated in cancer cells with a high demand… (More)
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