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Extremely Bothered

Known as: Extremely so, to the point where I could not take care of things 
A response indicating that an individual is or was extremely bothered, to the point where they could not take care of things.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial
Importance Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst formation in both kidneys… 
Highly Cited
2017
Highly Cited
2017
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
BACKGROUND AND OBJECTIVES Uremic pruritus in patients on hemodialysis is associated with depression, lower quality of life, and… 
Review
2017
Review
2017
Collagenase Clostridium histolyticum in the treatment of Peyronie’s disease: patient selection and perspectives
The safety and efficacy of the use of collagenase Clostridium histolyticum (CCH) for the treatment of Peyronie’s disease has been… 
2013
2013
Baseline characteristics from an ongoing phase 3 study of collagenase clostridium histolyticum in patients with Peyronie's disease.
INTRODUCTION Peyronie's disease (PD) is a localized penile collagen disorder of the tunica albuginea associated with significant… 
Review
2011
Review
2011
Oxycodone-related side effects: impact on degree of bother, adherence, pain relief, satisfaction, and quality of life.
OBJECTIVES Oxycodone immediate-release, alone or in combination (hereafter, oxycodone), is widely used to treat pain and is often… 
Highly Cited
2007
Highly Cited
2007
Lack of appetite in haemodialysis patients--associations with patient characteristics, indicators of nutritional status and outcomes in the international DOPPS.
BACKGROUND Identification of haemodialysis patients with problems related to lack of appetite should help prevent adverse… 
Review
2005
Review
2005
Depressive symptoms and mental health service utilization among persons with limb loss: results of a national survey.
Highly Cited
2004
Highly Cited
2004
Restless legs symptoms among incident dialysis patients: association with lower quality of life and shorter survival.
BACKGROUND Symptoms of restless legs are common among patients treated with long-term hemodialysis. We investigated the relation… 
Review
2004
Review
2004
Medical and self-care practices reported by women with urinary incontinence.
OBJECTIVES To determine the extent to which women with incontinence have been identified by physicians, the coping and treatment… 
Review
1998
Review
1998
Measuring quality of life in children with rhinoconjunctivitis.
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