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Extrapyramidal Disorders

Known as: EXTRAPYRAMIDAL SYNDROME, Extrapyramidal disorder, extrapyramidal disease 
A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Neurodegenerative disorders are characterized by progressive loss of selectively vulnerable populations of neurons, which… Expand
Review
2002
Review
2002
AbstractFollowing acceptance of clozapine as a superior antipsychotic agent with low risk of adverse extrapyramidal syndromes… Expand
Highly Cited
2000
Highly Cited
2000
Parkinson's disease is a common neurodegenerative syndrome characterized by loss of dopaminergic neurons in the substantia nigra… Expand
Highly Cited
1996
Highly Cited
1996
DOPAMINE receptors are the principal targets of drugs used in the treatment of schizophrenia1. Among the five mammalian dopamine… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND Metoclopramide hydrochloride, a neuroleptic dopamine receptor antagonist used to treat gastric ailments, is reported… Expand
Highly Cited
1992
Highly Cited
1992
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by… Expand
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Highly Cited
1987
Highly Cited
1987
Stereotactic thalamotomy of the thalamic nucleus ventralis intermedius (VIM) is routinely used for movement disorders. During… Expand
Highly Cited
1984
Highly Cited
1984
To identify the site and cause of airflow limitation in patients with parkinsonism, we tested pulmonary function in 27 patients… Expand
Highly Cited
1972
Highly Cited
1972
An adenylate cyclase that is activated specifically by low concentrations of dopamine has been demonstrated in homogenates of… Expand
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Highly Cited
1967
Highly Cited
1967
THE known biochemical abnormalities in Parkinson's disease consist of a decrease of melanin pigment in the substantia nigra1 , 2… Expand