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Excitatory Amino Acid Transporter 1

Known as: Transporter, SLC1A3, GLAST-1 Glutamate Aspartate Transporter, SLC1A3 Transporter 
A glial type glutamate plasma membrane transporter protein found predominately in ASTROCYTES. It is also expressed in HEART and SKELETAL MUSCLE and… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS) which initiates rapid signal… Expand
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Highly Cited
2018
Highly Cited
2018
As oxygen is essential for many metabolic pathways, tumour hypoxia may impair cancer cell proliferation1–4. However, the limiting… Expand
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2017
2017
  • X. Ding, Y. Li, +4 authors Yan Zhou
  • BMC Complementary and Alternative Medicine
  • 2017
  • Corpus ID: 19497048
BackgroundXiao Yao San (XYS) is an herbal prescription which is used in the treatment of depression for thousands of years from… Expand
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2015
2015
Background: The mechanism for transcriptional regulation of EAAT1 remains to be elucidated. Results: EGF-activated NF-κB is a… Expand
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Highly Cited
2013
Highly Cited
2013
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative disorders that are… Expand
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2011
2011
Objective: This study investigated the hypothesis that ceftriaxone preconditioning ameliorates brain damage in neonatal animals… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Recent data suggest that excessive glutamatergic signaling in the prefrontal cortex may contribute to the… Expand
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Highly Cited
2005
Highly Cited
2005
EAAT1 is a major glutamate transporter in the CNS and is required for normal neurotransmission and neuroprotection from… Expand
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2004
2004
The mechanisms of neuronal apoptosis in prion diseases are unclear. Experimental studies suggest that it may result from 2… Expand
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Highly Cited
2003
Highly Cited
2003
Excitatory amino acid transporter 1 (EAAT1) is one of the two glial glutamate transporters that clear the extracellular glutamate… Expand
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