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Excitatory Amino Acid Transporter 1

Known as: Transporter, SLC1A3, GLAST-1 Glutamate Aspartate Transporter, SLC1A3 Transporter 
A glial type glutamate plasma membrane transporter protein found predominately in ASTROCYTES. It is also expressed in HEART and SKELETAL MUSCLE and… 
National Institutes of Health

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In BloodProcess of secretionSLC1A3 geneagonists

Papers overview

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2020
2020
The 4b-4c loop of excitatory amino acid transporter 1 containing four critical residues essential for substrate transport
Abstract In the mammalians, the 4b-4c loop of excitatory amino acid transporters (EAATs) spans more than 50 amino-acid residues… 
2017
2017
Comparison of GCaMP3 and GCaMP6f for studying astrocyte Ca2+ dynamics in the awake mouse brain
In recent years it has become increasingly clear that astrocytes play a much more active role in neural processes than the… 
2014
2014
Investigating Substrate-Induced Motion between the Scaffold and Transport Domains in the Glutamate Transporter EAAT1
Excitatory amino acid transporter 1 plays an important role in keeping the synaptic glutamate concentration below neurotoxic… 
2014
2014
Cysteine mutagenesis reveals alternate proximity between transmembrane domain 2 and hairpin loop 1 of the glutamate transporter EAAT1
Excitatory amino acid transporter 1 (EAAT1) plays an important role in restricting the neurotoxicity of glutamate. Previous… 
2012
2012
The Accessibility in the External Part of the TM5 of the Glutamate Transporter EAAT1 Is Conformationally Sensitive during the Transport Cycle
Background Excitatory amino acid transporter 1 (EAAT1) is a glutamate transporter which is a key element in the termination of… 
2005
2005
50th Annual Meeting of the German Society of Neuropathology and Neuroanatomy, Clinical Neuropatholy - State of the Art, Graz, Austria, October 5-8, 2005
protein APP751 (KM670/671NL and V717I) and presenilin-1 (overexpressing M146L; or knocked-in M233T and L235P mutations, PS1KI… 
2004
2004
Expression of Excitatory Amino Acid Transporter‐1 (EAAT‐1) in Brain Macrophages and Microglia of Patients with Prion Diseases
The mechanisms of neuronal apoptosis in prion diseases are unclear. Experimental studies suggest that it may result from 2… 
1998
1998
Un mécanisme inédit d'épissage aberrant d'un ARN messager à l'origine des formes sporadiques de sclérose latérale amyotrophique.
La sclérose latérale amyotrophique (SLA, maladie de Charcot parfois aussi appelée maladie de Lou Gerhig par les Anglo-Saxons) est… 
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