Euphylong
National Institutes of Health
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It has been recognized recently that theophylline possesses anti-inflammatory effects that could be of clinical interest in…
In a multiple-dose crossover study in 18 healthy male volunteers the steady-state pharmacokinetics of Euphylong, which has been…
24 patients with COPD and delta FEV1 greater than 15% were included in a double-blind crossover study. 7 dropouts due to…
This contribution attempts to relate the in-vitro drug release properties of theophylline from Euphylong pellets to serum…
Euphylong is a sustained-release product consisting of encapsulated pellets covered with a porous membrane. Since the mechanism…
Euphylong is a new anhydrous theophylline sustained-release pellet formulation developed for once-daily administration in the…
Although bioequivalence between products has gained considerable importance over the last few years, the concept has not yet been…
In view of the large interindividual differences in theophylline clearance and the narrow therapeutic range it is essential to…
Three separate single-dose, randomized, cross-over studies in normal, healthy volunteers were performed to investigate the…
In a randomized, multiple-dose, cross-over study, serum theophylline concentrations (STC) were compared in 12 healthy volunteers…