Eukaryotic Translation Initiation Factor 2 Subunit 1
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It is not known how influenza A viruses, important human pathogens, counter PKR activation, a crucial host antiviral response… Expand Mice were subjected to 60 min occlusion of the left middle cerebral artery (MCA) followed by 1–6 h of reperfusion. Tissue samples… Expand A family of protein kinases regulates translation in response to different cellular stresses by phosphorylation of the alpha… Expand ABSTRACT Phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF-2α) is a well-characterized mechanism regulating… Expand In response to different cellular stresses, a family of protein kinases regulates translation by phosphorylation of the alpha… Expand ABSTRACT Hepatitis C virus (HCV) is prevalent worldwide and has become a major cause of liver dysfunction and hepatocellular… Expand ABSTRACT In cells infected with the herpes simplex virus 1 (HSV-1) recombinant R3616 lacking both copies of the γ134.5 gene, the… Expand ABSTRACT In herpes simplex virus-infected cells, viral γ134.5 protein blocks the shutoff of protein synthesis by activated… Expand Several translation initiation factors in mammals and yeast are regulated by phosphorylation. The phosphorylation state of these… Expand The phosphorylation of purified protein synthesis factors catalyzed by protein kinase preparations isolated from interferon… Expand