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Eukaryotic Translation Initiation Factor 2 Subunit 1

Known as: Eukaryotic Translation Initiation Factor 2 Subunit Alpha, eIF-2alpha, eIF-2-alpha 
Eukaryotic translation initiation factor 2 subunit 1 (315 aa, ~36 kDa) is encoded by the human EIF2S1 gene. This protein plays a role in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Protein kinases (PKs) play an important role in the development and progression of cancer by regulating cell growth, survival… Expand
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2005
2005
Vesicular stomatitis virus (VSV) is a rhabdovirus which causes acute encephalitis in mice after intranasal infection. Because… Expand
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Highly Cited
2005
Highly Cited
2005
The gamma(1)34.5 protein of herpes simplex virus (HSV) plays a crucial role in virus infection. Although the double-stranded RNA… Expand
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Highly Cited
2000
Highly Cited
2000
A family of protein kinases regulates translation in response to different cellular stresses by phosphorylation of the alpha… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF-2alpha) is a well-characterized mechanism regulating… Expand
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Highly Cited
2000
Highly Cited
2000
In response to different cellular stresses, a family of protein kinases regulates translation by phosphorylation of the alpha… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT In response to various environmental stresses, eukaryotic cells down-regulate protein synthesis by phosphorylation of… Expand
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Highly Cited
1998
Highly Cited
1998
In herpes simplex virus-infected cells, viral gamma134.5 protein blocks the shutoff of protein synthesis by activated protein… Expand
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Highly Cited
1998
Highly Cited
1998
In cells infected with the herpes simplex virus 1 (HSV-1) recombinant R3616 lacking both copies of the gamma134.5 gene, the… Expand
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Highly Cited
1997
Highly Cited
1997
Several translation initiation factors in mammals and yeast are regulated by phosphorylation. The phosphorylation state of these… Expand
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