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Eukaryotic Translation Initiation Factor 2 Subunit 1

Known as: Eukaryotic Translation Initiation Factor 2 Subunit Alpha, eIF-2alpha, eIF-2-alpha 
Eukaryotic translation initiation factor 2 subunit 1 (315 aa, ~36 kDa) is encoded by the human EIF2S1 gene. This protein plays a role in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
It is not known how influenza A viruses, important human pathogens, counter PKR activation, a crucial host antiviral response… Expand
Highly Cited
2001
Highly Cited
2001
Mice were subjected to 60 min occlusion of the left middle cerebral artery (MCA) followed by 1–6 h of reperfusion. Tissue samples… Expand
Highly Cited
2000
Highly Cited
2000
A family of protein kinases regulates translation in response to different cellular stresses by phosphorylation of the alpha… Expand
Highly Cited
2000
Highly Cited
2000
  • Ruojing Yang, S. A. Wek, R. Wek
  • Molecular and Cellular Biology
  • 2000
  • Corpus ID: 2129787
ABSTRACT Phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF-2α) is a well-characterized mechanism regulating… Expand
Highly Cited
2000
Highly Cited
2000
In response to different cellular stresses, a family of protein kinases regulates translation by phosphorylation of the alpha… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT Hepatitis C virus (HCV) is prevalent worldwide and has become a major cause of liver dysfunction and hepatocellular… Expand
Highly Cited
1998
Highly Cited
1998
ABSTRACT In cells infected with the herpes simplex virus 1 (HSV-1) recombinant R3616 lacking both copies of the γ134.5 gene, the… Expand
Highly Cited
1998
Highly Cited
1998
ABSTRACT In herpes simplex virus-infected cells, viral γ134.5 protein blocks the shutoff of protein synthesis by activated… Expand
Highly Cited
1997
Highly Cited
1997
Several translation initiation factors in mammals and yeast are regulated by phosphorylation. The phosphorylation state of these… Expand
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Highly Cited
1979
Highly Cited
1979
  • C. Samuel
  • Proceedings of the National Academy of Sciences…
  • 1979
  • Corpus ID: 1035600
The phosphorylation of purified protein synthesis factors catalyzed by protein kinase preparations isolated from interferon… Expand
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