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Eukaryotic Initiation Factor-5

Known as: Peptide Initiation Factor EIF-5, Eukaryotic Initiation Factor 5, Peptide Initiation Factor EIF 5 
A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

EIF5 wt AlleleGTP Phosphohydrolase Activators
In BloodProcess of secretionagonistsantagonists & inhibitors
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Narrower (1)

Krasavietz protein, Drosophila

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.
Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves… Expand
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2006
2006
Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors.
Eukaryotic initiation factor 5 (eIF5) plays multiple roles in translation initiation. Its N-terminal domain functions as a GTPase… Expand
2006
2006
The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5.
The carboxy-terminal domain (CTD) of eukaryotic initiation factor 5 (eIF5) plays a central role in the formation of the… Expand
Highly Cited
1997
Highly Cited
1997
GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae.
We have isolated and characterized two suppressor genes, SUI4 and SUI5, that can initiate translation in the absence of an AUG… Expand
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Highly Cited
1991
Highly Cited
1991
Function of eukaryotic initiation factor 5 in the formation of an 80 S ribosomal polypeptide chain initiation complex.
Eukaryotic initiation factor 5 (eIF-5), isolated from rabbit reticulocyte lysates, is a monomeric protein of 58-62 kDa. The… Expand
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1989
1989
Further characterization of eukaryotic initiation factor 5 from rabbit reticulocytes. Immunochemical characterization and phosphorylation by casein kinase II.
Eukaryotic initiation factor (eIF)-5, isolated from rabbit reticulocyte lysates, is a monomeric protein of Mr = 58,000-62,000… Expand
1987
1987
Characterization of eukaryotic initiation factor 5 from rabbit reticulocytes. Evidence that the initiation factor is a monomeric protein of Mr of about 58,000-62,000.
Eukaryotic initiation factor 5 (eIF-5) has been purified from the ribosomal salt-wash proteins of rabbit reticulocyte lysates… Expand
1985
1985
Eukaryotic initiation factor 5 from calf liver is a single polypeptide chain protein of Mr = 62,000.
Eukaryotic initiation factor 5 (eIF-5), which specifically catalyzes the joining of a 60 S ribosomal subunit to a 40 S initiation… Expand
1981
1981
The purification and characterization of multiple forms of protein synthesis eukaryotic initiation factors 2, 3, and 5 from rabbit reticulocytes.
Eukaryotic initiation factors 2, 3, and 5 (eIF-2, eIF-3, and eIF-5) each were purified or fractionated into a number of forms… Expand
1979
1979
Role of eukaryotic initiation factor 5 in the formation of 80 S initiation complexes.
The function of eukaryotic initiation factor 5 (eIF-5) from rabbit reticulocyte lysate has been studied by sucrose gradient… Expand
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