Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Ethyol

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Amifostine (Ethyol®) is a cytoprotective drug approved for the reduction of xerostomia in head and neck cancer when administered… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
Review
2003
Review
2003
The chemo- and radioprotectant drug amifostine (Ethyol; MedImmune, Inc, Gaithersburg, MD) is approved for intravenous (IV… Expand
Highly Cited
2002
Highly Cited
2002
Amifostine (Ethyol) has been evaluated clinically as a radioprotective agent for the prevention of xerostomia and mucositis for… Expand
Highly Cited
2000
Highly Cited
2000
Purpose: Amifostine (WR-2721), a phosphorylated aminothiol pro-drug which is an analogue of cysteamine, is a selective… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
Highly Cited
1997
Highly Cited
1997
The main metabolites of the cytoprotective drug Ethyol (Amifostine, WR-2721) are the thiol WR-1065 and the disulphide WR-33278… Expand
Review
1996
Review
1996
Amifostine (Ethyol) administered to cancer patients is rapidly cleared from plasma by a biphasic decay with an alpha half-life… Expand
1996
1996
Cultured neonatal rat heart myocytes form a synchronously-contracting cell syncytium from one to two days after isolation… Expand
Review
1994
Review
1994
Amifostine (WR-2721, S-2 [3-aminopropylamino]-ethylphosphorothioic acid; Ethyol, US Bioscience, Inc. West Conshohocken, PA… Expand
Highly Cited
1994
Highly Cited
1994
This study investigated the metabolism of the radio- and chemoprotector compound, WR-2721 [amifostine; s-2-(3- aminopropylamino… Expand
Review
1994
Review
1994
  • R. Capizzi
  • Seminars in oncology
  • 1994
  • Corpus ID: 43759659
The rationale for the clinical trials with amifostine (Ethyol, US Bioscience, Inc, West Conshohocken, PA) is based on an… Expand