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Ethyol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Amifostine (Ethyol®) is a cytoprotective drug approved for the reduction of xerostomia in head and neck cancer when administered… Expand
Review
2003
Review
2003
The chemo- and radioprotectant drug amifostine (Ethyol; MedImmune, Inc, Gaithersburg, MD) is approved for intravenous (IV… Expand
Highly Cited
2002
Highly Cited
2002
Amifostine (Ethyol) has been evaluated clinically as a radioprotective agent for the prevention of xerostomia and mucositis for… Expand
Highly Cited
2000
Highly Cited
2000
Purpose: Amifostine (WR-2721), a phosphorylated aminothiol pro-drug which is an analogue of cysteamine, is a selective… Expand
Highly Cited
1997
Highly Cited
1997
The main metabolites of the cytoprotective drug Ethyol (Amifostine, WR-2721) are the thiol WR-1065 and the disulphide WR-33278… Expand
Review
1996
Review
1996
Amifostine (Ethyol) administered to cancer patients is rapidly cleared from plasma by a biphasic decay with an alpha half-life… Expand
1996
1996
Cultured neonatal rat heart myocytes form a synchronously-contracting cell syncytium from one to two days after isolation… Expand
Review
1994
Review
1994
Amifostine (WR-2721, S-2 [3-aminopropylamino]-ethylphosphorothioic acid; Ethyol, US Bioscience, Inc. West Conshohocken, PA… Expand
Highly Cited
1994
Highly Cited
1994
This study investigated the metabolism of the radio- and chemoprotector compound, WR-2721 [amifostine; s-2-(3- aminopropylamino… Expand
Review
1994
Review
1994
The rationale for the clinical trials with amifostine (Ethyol, US Bioscience, Inc, West Conshohocken, PA) is based on an… Expand