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Cytogenetic evaluation and DNA interaction studies of the food colorants amaranth, erythrosine and tartrazine.
Food coloring agents, amaranth, erythrosine and tartrazine have been tested at 0.02-8mM in human peripheral blood cells in vitro, in order to investigate their genotoxic, cytotoxic and cytostaticExpand
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DNA damage and chromosomal aberrations in various types of male factor infertility.
OBJECTIVE To understand and delineate the nature and level of DNA damage in association to semen parameters in infertile men. DESIGN A prospective experimental study. SETTING AlexandroupolisExpand
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Supplementation of melatonin protects human lymphocytes in vitro from the genotoxic activity of melphalan.
Melatonin (MLT) is a natural oncostatic factor of the human body as well as an antioxidant thus protects the nuclear DNA from oxidative damage. It also has the ability to reduce the side effects ofExpand
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Effect of maternal smoking during pregnancy on fetus: a cytogenetic perspective
Abstract Objective: The examination of the genotoxic, cytostatic and cytotoxic effects of smoking during pregnancy. Method: Lymphocyte cultures of peripheral blood were received from 20 women whoExpand
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Cytogenetic evaluation of pre-pregnancy smoking in maternal and newborn lymphocytes.
OBJECTIVE To study cytogenetic damage in order to estimate the effect of pre-pregnancy smoking on pregnant women and their foetuses. STUDY DESIGN Lymphocyte cultures were obtained from peripheralExpand
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Genotoxic, cytostatic, antineoplastic and apoptotic effects of newly synthesized antitumour steroidal esters.
In this study, we have investigated the genotoxic, cytostatic, antineoplastic and apoptotic effects of three newly synthesized modified steroidal esters, having as alkylating agentExpand
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Evidence of increased chromosomal instability in infertile males after exposure to mitomycin C and caffeine.
AIM To evaluate the genetic instability of 11 fertile and 25 infertile men. METHODS The methodology of sister chromatid exchanges (SCEs) was applied to cultures of peripheral blood lymphocytes, andExpand
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Toxic organic substances and marker compounds in size-segregated urban particulate matter - Implications for involvement in the in vitro bioactivity of the extractable organic matter.
Toxic organic substances and polar organic marker compounds, i.e. polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), polybrominated diphenyl ethers (PBDEs), polycyclic aromaticExpand
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Antineoplastic and cytogenetic effects of chlorpromazine on human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo
The inhibitory effect of phenothiazines in tumor growth and cancer cell proliferation in vitro and in vivo has been established. These reports motivated us to investigate the genotoxic, cytotoxic,Expand
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In vitro cellular toxicity induced by extractable organic fractions of particles exhausted from urban combustion sources - Role of PAHs.
The bioactivity of the extractable organic matter (EOM) of particulate matter (PM) exhausted from major urban combustion sources, including residential heating installations (wood-burning fireplaceExpand
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