Ethylnitrosourea

Known as: N-ETHYL-N-NITROSOUREA, N-Nitroso-N-Ethylurea, Nitrosoethylurea 
A nitrosourea with potential antineoplastic activity. Used experimentally as a mutagen and carcinogen, ethylnitrosourea alkylates DNA and proteins… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Type I interferons (IFNs) are central regulators of the innate and adaptive immune responses to viral and bacterial infections… (More)
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Highly Cited
2008
Highly Cited
2008
X-chromosome inactivation is the mammalian dosage compensation mechanism by which transcription of X-linked genes is equalized… (More)
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Highly Cited
2007
Highly Cited
2007
Using a forward genetics ENU mutagenesis screen for recessive mutations that affect circadian rhythmicity in the mouse, we… (More)
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Highly Cited
2007
Highly Cited
2007
OPA1 is a ubiquitously expressed, nuclear dynamin-related GTPase, targeted to the inner mitochondrial membrane, which plays a… (More)
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Highly Cited
2007
Highly Cited
2007
The development of the mammalian brain is dependent on extensive neuronal migration. Mutations in mice and humans that affect… (More)
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Review
2006
Review
2006
Classical genetic methods, driven by phenotype rather than hypotheses, generally permit the identification of all proteins that… (More)
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Highly Cited
2005
Highly Cited
2005
The retinotectal projection is a premier model system for the investigation of molecular mechanisms that underlie axon… (More)
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Highly Cited
2003
Highly Cited
2003
Intraflagellar transport (IFT) proteins were first identified as essential factors for the growth and maintenance of flagella in… (More)
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Highly Cited
2000
Highly Cited
2000
As the human genome project approaches completion, the challenge for mammalian geneticists is to develop approaches for the… (More)
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Highly Cited
1996
Highly Cited
1996
Anaphase initiation has been postulated to be controlled through the ubiquitin-dependent proteolysis of an unknown inhibitor… (More)
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