Ethambutol

Known as: (+)-ethambutol, Ethambutol [Chemical/Ingredient], Etambutol 
An antibiotic with bacteriostatic, antimicrobial and antitubercular properties. Ethambutol interferes with the biosynthesis of arabinogalactan, a… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
BACKGROUND New treatments are needed to shorten the time required to cure tuberculosis and to treat drug-resistant strains. The… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND We explored the association between antituberculosis drug pharmacokinetics and treatment outcomes among patients with… (More)
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Highly Cited
2006
Highly Cited
2006
Evaluation of sources of pharmacokinetic variation can facilitate optimization of tuberculosis treatment regimens by… (More)
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Highly Cited
2000
Highly Cited
2000
Ethambutol (EMB) is a central component of drug regimens used worldwide for the treatment of tuberculosis. To gain insight into… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT No large-scale study has investigated the impact of multidrug-resistant tuberculosis (TB) on the outcome of standard… (More)
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Highly Cited
1997
Highly Cited
1997
Ethambutol [(S,S')-2,2'-(ethylenediimino)di-1-butanol; EMB], is a first-line drug used to treat tuberculosis. To gain insight… (More)
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Highly Cited
1997
Highly Cited
1997
Ethambutol (EMB), a frontline antituberculous drug, targets the mycobacterial cell wall, a unique structure among prokaryotes… (More)
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Highly Cited
1996
Highly Cited
1996
The antimycobacterial compound ethambutol [Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol] is used to treat tuberculosis as well… (More)
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Highly Cited
1995
Highly Cited
1995
The effect of ethambutol (EMB) is primarily on polymerization steps in the biosynthesis of the arabinan component of cell wall… (More)
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Highly Cited
1989
Highly Cited
1989
Ethambutol at 3.0 micrograms/ml inhibited the transfer of label from D-[14C]glucose into the D-arabinose residue of… (More)
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