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Estrogen Receptors

Known as: oestrogen receptor, Receptors, Estrogen [Chemical/Ingredient], estrogen receptor (ER) 
Widely expressed human Estrogen Receptors (NR3 Family) are cytoplasmic hormone-activated receptors that act as nuclear transcription factors composed… 
National Institutes of Health

Related topics

Related topics

48 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Narrower (13)

ERR protein, DrosophilaERR1 proteinESRRB protein, humanESRRG protein, human

Broader (1)

steroid hormone receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Estrogen Rapidly Enhances Incisional Pain of Ovariectomized Rats Primarily through the G Protein-Coupled Estrogen Receptor
It has become increasingly apparent that the pain threshold of females and males varies in an estrogen dependent manner. To… 
Review
2004
Review
2004
Estrogen receptor mutations in human disease.
As early as the 1800s, the actions of estrogen have been implicated in the development and progression of breast cancer. The… 
Review
2003
Review
2003
Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
Antiestrogens include agents such as tamoxifen, toremifene, raloxifene, and fulvestrant. Currently, tamoxifen is the only drug… 
Review
2001
Review
2001
Role of estrogen receptor beta in estrogen action.
There was a time when the classification of sex hormones was simple. Androgens were male and estrogens female. What remains true… 
Highly Cited
1999
Highly Cited
1999
Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.
The effectiveness of estrogens in stimulating gene transcription mediated by the estrogen receptor (ER) appears to depend on ER… 
Highly Cited
1998
Highly Cited
1998
Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross‐talk with estrogen receptor
The molecular mechanisms by which ovarian hormones stimulate growth of breast tumors are unclear. It has been reported previously… 
Highly Cited
1989
Highly Cited
1989
The human estrogen receptor has two independent nonacidic transcriptional activation functions
Highly Cited
1984
Highly Cited
1984
Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells
Although it is widely accepted that specific intracellular receptor proteins are involved in the oestrogenic regulation of gene… 
Highly Cited
1984
Highly Cited
1984
Nuclear localization of unoccupied oestrogen receptors
According to the current model of steroid hormone action oestrogen is thought to bind to its receptor in the cytoplasm of target… 
Highly Cited
1980
Highly Cited
1980
The value of estrogen and progesterone receptors in the treatment of breast cancer
The estrogen receptor (ER) assay has become a standard practice in the management of advanced breast cancer. Tumors lacking ER… 
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