FAQ

Estrogen Receptors

Known as: oestrogen receptor, Receptors, Estrogen [Chemical/Ingredient], estrogen receptor (ER) 
Widely expressed human Estrogen Receptors (NR3 Family) are cytoplasmic hormone-activated receptors that act as nuclear transcription factors composed… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
0500100019682018

Related topics

Related topics

47 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation
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Narrower (13)

ERR protein, DrosophilaERR1 proteinESRRB protein, humanESRRG protein, human
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Broader (1)

steroid hormone receptor

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Estrogen Receptors
Cell Differentiation process
Cell Proliferation
Estrogens
Signal Transduction
physiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
A transmembrane intracellular estrogen receptor mediates rapid cell signaling.
The steroid hormone estrogen regulates many functionally unrelated processes in numerous tissues. Although it is traditionally… (More)
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Highly Cited
2005
Highly Cited
2005
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
Although nonclassical estrogen actions initiated at the cell surface have been described in many tissues, the identities of the… (More)
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Highly Cited
2005
Highly Cited
2005
Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1
Estrogen plays an essential physiologic role in reproduction and a pathologic one in breast cancer. The completion of the human… (More)
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Highly Cited
2003
Highly Cited
2003
Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter
Transcriptional activation of a gene involves an orchestrated recruitment of components of the basal transcription machinery and… (More)
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Highly Cited
2000
Highly Cited
2000
Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription
Many cofactors bind the hormone-activated estrogen receptor (ER), yet the specific regulators of endogenous ER-mediated gene… (More)
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Highly Cited
1998
Highly Cited
1998
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal… (More)
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Highly Cited
1998
Highly Cited
1998
The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen
Ligand-dependent activation of transcription by nuclear receptors (NRs) is mediated by interactions with coactivators. Receptor… (More)
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Highly Cited
1998
Highly Cited
1998
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Estrogens influence the differentiation and maintenance of reproductive tissues and affect lipid metabolism and bone remodeling… (More)
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Highly Cited
1997
Highly Cited
1997
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.
The rat estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal ligand binding domain… (More)
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Highly Cited
1997
Highly Cited
1997
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites.
The transactivation properties of the two estrogen receptors, ERalpha and ERbeta, were examined with different ligands in the… (More)
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