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Equilin

Known as: Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-, 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one, Equilin [Chemical/Ingredient] 
An estrogenic steroid produced by HORSES. It has a total of four double bonds in the A- and B-ring. High concentration of euilin is found in the… Expand
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (6)

2-hydroxyequilin2-methoxyequilin4-hydroxy-equilin4-methoxyequilin
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In BloodProcess of secretionagonistsanalogs & derivatives
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Molecular characterization of a B-ring unsaturated estrogen: Implications for conjugated equine estrogen components of Premarin
Conjugated equine estrogens (CEEs) are routinely used for hormone replacement therapy (HRT), making it important to understand… Expand
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Highly Cited
2005
Highly Cited
2005
Mixtures of estrogenic contaminants in bile of fish exposed to wastewater treatment works effluents.
Most effluents from wastewater treatment works (WwTWs) contain estrogenic chemicals that include steroidal estrogens and… Expand
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Review
2001
Review
2001
Assessment of Hormonally Active Agents in the Reproductive Tract of Female Nonhuman Primates
Using the ovariectomized macaque model of postmenopausal women's health, we investigated the effects of long-term treatments (5… Expand
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1999
1999
The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
The risk factors for women developing breast and endometrial cancers are all associated with a lifetime of estrogen exposure… Expand
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1999
1999
Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Excess 17beta-estradiol (E2), the most potent of human estrogens, is known to act as a stimulus for the growth of breast tumors… Expand
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1999
1999
A boron-containing estrogen mimic.
A prototype of a new class of 2,3,1-benzodiazaborine-based estrogen mimics is described. 1,2-Dihydro-1,6-dihydroxy-2-(2-methoxy-6… Expand
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Review
1998
Review
1998
Selective Estrogen Receptor Modulators: An Alternative to Hormone Replacement Therapy
Abstract Estrogen is a key regulatory hormone, which in addition to its role in reproduction, affects a number of physiological… Expand
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1998
1998
Estrogens, progestins, and coronary artery reactivity in atherosclerotic monkeys
It has been known for many years that sex hormones modulate vasodilator responses of arteries supplying the uterus with blood… Expand
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1997
1997
Equilin, a Principal Component of the Estrogen Replacement Therapy Premarin, Increases the Growth of Cortical Neurons via an NMDA Receptor-Dependent Mechanism
Regulation of both the outgrowth and the survival of neurons involved in cognitive function can have a significant impact on the… Expand
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Highly Cited
1997
Highly Cited
1997
Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures
A growing body of evidence supports the hypothesis that estrogens may be beneficial in Alzheimer's disease and other… Expand
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