Equilibrative-Nucleoside Transporter 2

Known as: Equilibrative Nucleoside Transporter 2, SLC29A2, Equilibrative, Nitrobenzylmercaptopurine Riboside (NBMPR)-Insensitive Nucleoside Transporter 
Equilibrative nucleoside transporter 2 (456 aa, ~50 kDa) is encoded by the human SLC29A2 gene. This protein plays a role in nucleoside transport for… (More)
National Institutes of Health

Related topics

Related topics

20 relations
Basolateral Sorting SignalCell ProliferationCellular MembraneIn Blood
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.
INTRODUCTION Studies have shown that ticagrelor has a further adenosine-mediated mechanism of action in addition to its potent… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia.
BACKGROUND & AIMS The surface of the intestinal mucosa is particularly prone to hypoxia-induced inflammation. Previous studies… (More)
  • figure 1
  • figure 3
  • figure 7
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer.
BACKGROUND & AIMS The human equilibrative nucleoside transporter (hENT1) protein transports gemcitabine into cells. Small… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant gemcitabine therapy in resected pancreatic adenocarcinoma.
PURPOSE Gemcitabine is a promising adjuvant treatment for patients with resected pancreatic adenocarcinoma and its use in… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Review
2008
Review
2008
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins.
1. The human (h) SLC29 family of integral membrane proteins is represented by four members, designated equilibrative nucleoside… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
Extracellular adenosine (Ado) has been implicated as central signaling molecule during conditions of limited oxygen availability… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2004
Review
2004
The equilibrative nucleoside transporter family, SLC29
The human SLC29 family of proteins contains four members, designated equilibrative nucleoside transporters (ENTs) because of the… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance.
Membrane transporters and channels (collectively the transportome) govern cellular influx and efflux of ions, nutrients, and… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Nucleoside transporter profiles in human pancreatic cancer cells: role of hCNT1 in 2',2'-difluorodeoxycytidine- induced cytotoxicity.
PURPOSE Concentrative nucleoside transporter (CNT) 1, CNT3, equilibrative nucleoside transporter (ENT) 1, and, to a lesser extent… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.
BACKGROUND Gemcitabine, a pyrimidine analogue of deoxycytidine, is an anticancer nucleoside drug that requires functional plasma… (More)
Is this relevant?