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Equilenin

Known as: Equilenin [Chemical/Ingredient], Estra-1,3,5,7,9-pentaen-17-one, 3-hydroxy- 
An estrogenic steroid produced by HORSES. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the… 
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (7)

17-dihydroequilenin2-hydroxyequilenin2-methoxyequilenin3-aminodesoxyequilenin
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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2004
2004
Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.
2003
2003
Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
Estrogen replacement therapy has been correlated with an increased risk for developing breast and endometrial cancers. One… 
2002
2002
Investigations into the biosynthetic pathways for classical and ring B-unsaturated oestrogens in equine placental preparations and allantochorionic tissues
Highly Cited
1999
Highly Cited
1999
The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
The risk factors for women developing breast and endometrial cancers are all associated with a lifetime of estrogen exposure… 
1997
1997
The influence of temperature on the multiple separation of estrogenic steroids using mobile phases modified with beta-cyclodextrin in high-performance liquid chromatography.
1989
1989
Orientation, accessibility, and mobility of equilenin bound to the active site of steroid isomerase.
The fluorescent aromatic steroid equilenin, which contains a beta-naphthol moiety, is bound by 3-oxo-delta 5-steroid isomerase… 
Review
1988
Review
1988
The saga of the ring B unsaturated equine estrogens.
THE RING B unsaturated estrogens, equilin, equilenin, 17α-dihydroequilin, 17α-dihydroequilenin, 17β-dihydroequilin, and 17… 
Highly Cited
1986
Highly Cited
1986
Excited-state proton transfer of equilenin and dihydroequilenin: interaction with bilayer vesicles.
The two-state excited-state proton-transfer process for d-equilenin [d-3-hydroxyestra-1,3,-5(10),6,8-pentaen-17-one] and… 
Highly Cited
1985
Highly Cited
1985
Estrogen 2- and 4-hydroxylase activity, catechol estrogen formation, and implications for estrogen carcinogenesis in the hamster kidney.
Estrogen 2- and 4-hydroxylase (ESH), a microsomal enzyme which mediates the formation of catechol estrogens, has been studied in… 
1976
1976
Human placental 3beta-hydroxysteroid dehydrogenase: delta5-isomerase. Demonstration of an intermediate in the conversion of 3beta-hydroxypregn-5-en-20-one to pregn-4-ene-3,20-dione.
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