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Epitopes

Known as: Epitopes [Chemical/Ingredient], Binding Determinants, Epitope 
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
National Institutes of Health

Related topics

Related topics

12 relations
Antibodies, Anti-IdiotypicAntibody AffinityAntigenic SpecificityChemical Structure

Broader (1)

Antigens

Narrower (1)

TAB9

Papers overview

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1987
1987
Receptor diversity of insulin-specific T cell lines from C57BL (H-2b) mice.
To characterize the T cell receptor repertoire in an immune response in which the Ia and nominal antigenic determinants are… 
Highly Cited
1986
Highly Cited
1986
Monoclonal antibody (H107) inhibiting IgE binding to Fc epsilon R(+) human lymphocytes.
A hybridoma-producing monoclonal antibody blocking the binding of human IgE to lymphocytes Fc receptor (Fc epsilon R) was… 
Highly Cited
1984
Highly Cited
1984
Immunologic characterization and molecular profile of carcinoembryonic antigen detected by monoclonal antibodies.
Four distinct monoclonal antibodies, which reacted with CEA preparations but not with nonspecific cross-reacting antigen or with… 
1982
1982
Antibodies to RNA from autoimmune NZB/NZW mice recognize a similar antigenic determinant and show a large idiotypic diversity.
We have identified two RNA-specific hybridoma autoantibodies in fusions of spleen cells from unimmunized NZB/NZW female mice with… 
Highly Cited
1979
Highly Cited
1979
Public antigenic determinant on a family of HLA-B molecules.
Serologic cross-reactivity among allelic gene products commonly occurs in the HLA complex, but the molecular basis of these… 
1978
1978
Masking of protein antigen by modification of amino groups with carbobenzoxychloride (benzyl chloroformate) and demasking by treatment with nonspecific protease.
Cryostat sections of various substrates were treated with carbobenzoxychloride in acetone to modify antigens. By applying… 
Highly Cited
1977
Highly Cited
1977
A methodology for the production of carbohydrate-specific antibody.
8-Methoxycarbonyloctyl glycosides are recommended as precursors for the preparation of artificial antigens that possess strongly… 
Highly Cited
1975
Highly Cited
1975
Specificity of the antibody response in inbred mice to bovine type I and type II collagen.
Mouse antibodies to soluble bovine skin (type I) collagen react with determinants which are located in the rigid triple-helical… 
Highly Cited
1971
Highly Cited
1971
Species-specific and interspecific antigenic determinants associated with the structural protein of feline C-type virus.
The group-specific protein of feline leukemia viruses has been isolated by isoelectric focusing. This protein has a molecular… 
1967
1967
N-and C-terminal Sequences of a Heavy Chain Disease Protein and its Genetic Implications
A VARIANT of myeloma has been described1,2; it is known as heavy chain disease, and is characterized by the presence of a…