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Epitopes

Known as: Epitopes [Chemical/Ingredient], Binding Determinants, Epitope 
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
National Institutes of Health

Related topics

Related topics

12 relations
Antibodies, Anti-IdiotypicAntibody AffinityAntigenic SpecificityChemical Structure

Broader (1)

Antigens

Narrower (1)

TAB9

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to… 
Highly Cited
2007
Highly Cited
2007
Prediction of linear B-cell epitopes using amino acid pair antigenicity scale
Summary.Identification of antigenic sites on proteins is of vital importance for developing synthetic peptide vaccines… 
Highly Cited
1999
Highly Cited
1999
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant.
Microparticles (MPs) resulting from vesiculation of platelets and other blood cells have been extensively documented in vitro and… 
Highly Cited
1998
Highly Cited
1998
Massive expansion of antigen-specific CD8+ T cells during an acute virus infection.
Highly Cited
1998
Highly Cited
1998
Coordinate regulation of complex T cell populations responding to bacterial infection.
Review
1997
Review
1997
Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy
Abstract Aberrant glycosylation is a hallmark of cancer cells. The blood group precursors T (Thomsen-Friedenreich) and Tn… 
Highly Cited
1994
Highly Cited
1994
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
The relationship between binding affinity for HLA class I molecules and immunogenicity of discrete peptide epitopes has been… 
Highly Cited
1991
Highly Cited
1991
Exact prediction of a natural T cell epitope
T lymphocytes recognize their antigen as peptides associated with major histocompatibility complex (MHC) molecules. Peptides… 
Highly Cited
1989
Highly Cited
1989
Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells
To understand the effect of human MHC class II polymorphism on antigen recognition, we analyzed the memory T cell response to… 
Highly Cited
1988
Highly Cited
1988
A sequence pattern common to T cell epitopes.
An analysis of the known cytotoxic and helper T cell epitopes has revealed similarity within their primary sequences. These… 
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