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Epitopes

Known as: Epitopes [Chemical/Ingredient], Binding Determinants, Epitope 
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The term bispecific antibody (bsAb) is used to describe a large family of molecules designed to recognize two different epitopes… Expand
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Review
2018
Review
2018
ABSTRACT Peptide-based anticancer vaccination aims at stimulating an immune response against one or multiple tumor-associated… Expand
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Review
2018
Review
2018
Vaccine design efforts against the human immunodeficiency virus (HIV) have been greatly stimulated by the observation that many… Expand
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Review
2017
Review
2017
Adaptive immunity is mediated by T- and B-cells, which are immune cells capable of developing pathogen-specific memory that… Expand
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Review
2017
Review
2017
Monoclonal antibodies are among the most clinically effective drugs used to treat cancer. However, their target repertoire is… Expand
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Highly Cited
2006
Highly Cited
2006
BackgroundB-cell epitopes are the sites of molecules that are recognized by antibodies of the immune system. Knowledge of B-cell… Expand
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Highly Cited
1994
Highly Cited
1994
The relationship between binding affinity for HLA class I molecules and immunogenicity of discrete peptide epitopes has been… Expand
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Highly Cited
1981
Highly Cited
1981
  • T. Hopp, K. Woods
  • Proceedings of the National Academy of Sciences…
  • 1981
  • Corpus ID: 677016
A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of… Expand
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Highly Cited
1981
Highly Cited
1981
The haemagglutinin glycoprotein of influenza virus is a trimer comprising two structurally distinct regions: a triple-stranded… Expand
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Highly Cited
1965
Highly Cited
1965
Two methods were used to demonstrate the presence of tumor-specific antigens in adenocarcinomata of the human colon: (a) rabbits… Expand
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