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Epitopes
Known as:
Epitopes [Chemical/Ingredient]
, Binding Determinants
, Epitope
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The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
National Institutes of Health
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Related topics
Related topics
12 relations
Antibodies, Anti-Idiotypic
Antibody Affinity
Antigenic Specificity
Chemical Structure
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Broader (1)
Antigens
Narrower (1)
TAB9
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
A. Walls
,
Young-Jun Park
,
M. Alexandra Tortorici
,
A. Wall
,
Andrew T. McGuire
,
D. Veesler
Cell
2020
Corpus ID: 212631502
Highly Cited
2020
Highly Cited
2020
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
Lihong Liu
,
Pengfei Wang
,
+21 authors
D. Ho
Nature
2020
Corpus ID: 220718498
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues, with devasting consequences for human lives…
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Highly Cited
2017
Highly Cited
2017
BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes
M. C. Jespersen
,
Bjoern Peters
,
M. Nielsen
,
P. Marcatili
Nucleic Acids Res.
2017
Corpus ID: 215779421
Abstract Antibodies have become an indispensable tool for many biotechnological and clinical applications. They bind their…
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Highly Cited
2008
Highly Cited
2008
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Julia V. Ponomarenko
,
H. Bui
,
+4 authors
Björn Peters
BMC Bioinformatics
2008
Corpus ID: 267798857
BackgroundReliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of…
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Highly Cited
2006
Highly Cited
2006
Improved method for predicting linear B-cell epitopes
J. Larsen
,
O. Lund
,
M. Nielsen
Immunome Research
2006
Corpus ID: 2341929
BackgroundB-cell epitopes are the sites of molecules that are recognized by antibodies of the immune system. Knowledge of B-cell…
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Highly Cited
2006
Highly Cited
2006
Prediction of continuous B‐cell epitopes in an antigen using recurrent neural network
S. Saha
,
Gajendra P.S. Raghava
Proteins: Structure, Function, and Bioinformatics
2006
Corpus ID: 8182012
B‐cell epitopes play a vital role in the development of peptide vaccines, in diagnosis of diseases, and also for allergy research…
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Highly Cited
1994
Highly Cited
1994
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
A. Sette
,
A. Vitiello
,
+14 authors
F. Chisari
Journal of Immunology
1994
Corpus ID: 10660381
The relationship between binding affinity for HLA class I molecules and immunogenicity of discrete peptide epitopes has been…
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Highly Cited
1981
Highly Cited
1981
Prediction of protein antigenic determinants from amino acid sequences.
T. Hopp
,
K. R. Woods
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 677016
A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of…
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Highly Cited
1981
Highly Cited
1981
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
I. Wilson
,
J. Skehel
,
D. Wiley
Nature
1981
Corpus ID: 4327688
The haemagglutinin glycoprotein of influenza virus is a trimer comprising two structurally distinct regions: a triple-stranded…
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Highly Cited
1965
Highly Cited
1965
DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES
P. Gold
,
S. Freedman
Journal of Experimental Medicine
1965
Corpus ID: 12356915
Two methods were used to demonstrate the presence of tumor-specific antigens in adenocarcinomata of the human colon: (a) rabbits…
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