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Antibody Affinity

Known as: antigen antibody affinity, Affinities, Antibody, Affinity, Antibody 
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (1)

Antibody Avidity

Broader (1)

Antigen-Antibody Reactions
Binding Sites, AntibodyEpitopesaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2019
Highly Cited
2019
Intradermal delivery of vaccine nanoparticles using hollow microneedle array generates enhanced and balanced immune response.
Highly Cited
2019
Highly Cited
2019
Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans
Several vaccines are approved in the United States for seasonal influenza vaccination every year. Here we compare the impact of… 
Highly Cited
2014
Highly Cited
2014
Heterologous Prime-Boost Vaccination with MF59-Adjuvanted H5 Vaccines Promotes Antibody Affinity Maturation towards the Hemagglutinin HA1 Domain and Broad H5N1 Cross-Clade Neutralization
In an open label clinical study (2007), MF59-adjuvanted hemagglutinin (HA) vaccine from H5N1-A/Vietnam/1194/2004 (clade 1) was… 
Highly Cited
2012
Highly Cited
2012
AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans
The role of Activation-Induced Cytidine Deaminase (AID) in somatic hypermutation and polyclonal antibody affinity maturation has… 
Highly Cited
2009
Highly Cited
2009
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease
Respiratory syncytial virus (RSV) is a leading cause of hospitalization in infants. A formalin-inactivated RSV vaccine was used… 
Highly Cited
2008
Highly Cited
2008
Lack of antibody affinity maturation due to poor Toll stimulation led to enhanced RSV disease
Respiratory syncytial virus (RSV) is a leading cause of hospitalization in infants. A formalin-inactivated RSV vaccine was used… 
2000
2000
Protection against measles virus-induced encephalitis by anti-mimotope antibodies: the role of antibody affinity.
Synthetic peptides mimicking a conformational B-cell epitope (M2) of the measles virus fusion protein (MVF) were used for the… 
Highly Cited
1999
Highly Cited
1999
Epitope Mapping of CCR5 Reveals Multiple Conformational States and Distinct but Overlapping Structures Involved in Chemokine and Coreceptor Function*
The chemokine receptor CCR5 is the major coreceptor for R5 human immunodeficiency virus type-1 strains. We mapped the epitope… 
Highly Cited
1998
Highly Cited
1998
Immunoglobulin specificity of TG19318: a novel synthetic ligand for antibody affinity purification
A synthetic ligand [TG19318], able to mimic protein A in the recognition of the immunoglobulin Fc portion, has been previously… 
Highly Cited
1988
Highly Cited
1988
Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin
Thirty-six monoclonal antibodies to the protective antigen protein of Bacillus anthracis exotoxin have been characterized for… 
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