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Epitope Mapping

Known as: Epitope Mappings, Mapping, Epitope, Mappings, Epitope 
Methods used for studying the interactions of antibodies with specific regions of protein antigens. Important applications of epitope mapping are… 
National Institutes of Health

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Related topics

5 relations
EpitopesProtein Structurenursing therapystandards characteristics

Broader (1)

Immunologic Techniques

Papers overview

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Highly Cited
2001
Highly Cited
2001
Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains.
Despite extensive experimental and clinical evidence demonstrating the critical role of flavocytochrome b558 (Cyt b) in the NADPH… 
1996
1996
Monoclonal antibodies against human immunodeficiency virus type 1 integrase: epitope mapping and differential effects on integrase activities in vitro
Human immunodeficiency virus type 1 (HIV-1) integrase (IN) catalyzes the integration of viral DNA into the host chromosome, an… 
Highly Cited
1995
Highly Cited
1995
Localization of multiple functional domains on human PECAM-1 (CD31) by monoclonal antibody epitope mapping.
PECAM-1, a cell adhesion molecule of the immunoglobulin gene (Ig) superfamily, has been implicated in white cell transmigration… 
Highly Cited
1994
Highly Cited
1994
Membrane Topology of the GluR1 Glutamate Receptor Subunit: Epitope Mapping by Site‐Directed Antipeptide Antibodies
Abstract: In order to define the membrane topology of the GluR1 glutamate receptor subunit, we have examined the location of… 
Highly Cited
1990
Highly Cited
1990
Heterologous expression and epitope mapping of a human small nuclear ribonucleoprotein-associated Sm-B'/B autoantigen.
The U snRNP associated B'/B polypeptides are primary targets of Sm autoantibodies in patients with systemic lupus erythematosus… 
Highly Cited
1988
Highly Cited
1988
Epitope mapping with a recombinant human 68-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human autoimmune sera.
Several cDNA fragments encoding parts of the (U1)RNP specific 68-kDa autoantigen were expressed in Escherichia coli and the… 
Highly Cited
1988
Highly Cited
1988
Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein.
The human immunodeficiency virus type 1 (HIV-1) uses the CD4 protein as a receptor for infection of susceptible cells. A… 
Highly Cited
1988
Highly Cited
1988
A rapid method of epitope mapping. Application to the study of immunogenic domains and to the characterization of various forms of rabbit progesterone receptor.
A method is described to map contiguous epitopes recognized by monoclonal antibodies in the case when the cDNA for a protein has… 
Highly Cited
1986
Highly Cited
1986
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicry.
Human immunodeficiency virus (HIV), the retrovirus that causes the acquired immunodeficiency syndrome, is cytopathic for CD4+ T… 
Highly Cited
1982
Highly Cited
1982
Monoclonal antibody (B27M2) subdividing HLA-B27.
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