Epipodophyllotoxin

Known as: Epipodophyllotoxin Compound 
An alkaloid isolated or derived synthetically from Podophyllum peltatum that can bind to and inhibit topoisomerase II and its function in ligating… (More)
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Plant-derived compounds have been an important source of several clinically useful anti-cancer agents. These include vinblastine… (More)
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Highly Cited
1999
Highly Cited
1999
PURPOSE The incidence of secondary leukemia after epipodophyllotoxin treatment and the relationship between epipodophyllotoxin… (More)
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Review
1998
Review
1998
The major established cause of acute myeloid leukemia (AML) in the young is cancer chemotherapy. There are two forms of treatment… (More)
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Review
1997
Review
1997
Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment… (More)
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1995
1995
To define better the risk of epipodophyllotoxin-related acute myeloid leukemia (AML) after extended follow-up and to assess… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Treatment of cancer with the epipodophyllotoxins (etoposide and teniposide) has been linked to the… (More)
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Review
1991
Review
1991
Thirty-seven children and adults who developed acute nonlymphocytic leukemia after the administration of chemotherapy that… (More)
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Highly Cited
1986
Highly Cited
1986
Recent evidence indicates that type II DNA topoisomerases mediate epipodophyllotoxin-induced DNA damage and may be intrinsic to… (More)
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1985
1985
This laboratory and others previously proposed that the antitumor effects of the epipodophyllotoxin compounds are based on their… (More)
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Highly Cited
1984
Highly Cited
1984
Epipodophyllotoxins are an important new class of anticancer agents which include the compounds VM-26 (teniposide) and VP-16… (More)
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