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Prolactin as a modulator of lymphocyte responsiveness provides a possible mechanism of action for cyclosporine.
Lymphocyte responsiveness in rats was found to depend on serum prolactin levels. Blocking pituitary prolactin release with bromocriptine severely reduces lymphocyte reactivity in vitro (mixedExpand
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An evaluation of ultrasonic therapy for temporomandibular joint dysfunction.
Abstract In a study of 100 patients, ultrasonic therapy alone was not effective in relieving symptoms of temporomandibular joint dysfunction and associated symptoms of muscle spasm. However, it didExpand
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Glia cell response to bacterial lipopolysaccharide: Effect on nucleotide synthesis, its genetic control and definition of the active principle
Cell types sensitive to lipopolysaccharides (LPS) include macrophages, polymorphonuclear leukocytes, platelets, B-lymphocytes and fibroblasts. Earlier observations that during endotoxemia orExpand
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Studies on the division cycle of mammalian cells. 3. Preparation of synchronously dividing cell populations by isotonic sucrose gradient centrifugation.
Abstract A method of preparing synchronous cell cultures is presented which is based on a selection of postmitotic cells by density gradient centrifugation. Gradients were prepared by appropriateExpand
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Effect of an epipodophyllotoxin derivative (VP 16-213) on macromolecular synthesis and mitosis in mastocytoma cells in vitro.
The influence of the semisynthetic epipodophyllotoxin derivative VP 16-213 on different cellular and biochemical parameters was determined with the use of suspension cultures of a murine mastocytoma.Expand
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In vitro stimulation of glia cells by a lymphocyteproduced factor
The factors responsible for the activation of astrocytes surrounding inflammatory brain tissues are unknown. The present study was designed to examine the ability of lymphocytes to produce astrocyteExpand
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The effects of cyclosporins on the cell cycle of t-lymphoid cell lines.
Abstract Cyclosporin A (CsA) is a cyclic endecapeptide of fungal origin displaying strong immunosuppressive properties. CsA and another active member of the cyclosporin (Cs) family, but not anExpand
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STUDIES ON LIVER REGENERATION: I. 131IODODEOXYURIDINE AS A PRECURSOR of DNA IN NORMAL and REGENERATING RAT LIVER
Abstract. 131Iododeoxyuridine (131IDU) was injected into normal and partially hepatectomized rats, and the specificity of incorporation of this thymidine analogue into liver DNA was determined 2, 24Expand
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Interference of cyclosporin with lymphocyte activation: blockage of the mitogen-induced increases of lysosomal and mitochondrial activities.
Mouse lymphocytes were activated by a mitogenic dose of concanavalin A and analysed by flow cytometry to monitor the increases of mitochondrial activity (using rhodamine 123 as probe) and ofExpand
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Studies on the division cycle of mammalian cells. VI. DNA polymerase activities in partially synchronous suspension cultures.
Abstract Partially synchronous cultures of a murine mastocytoma were prepared by centrifugation of cells in isotonic sucrose gradients and reincubation of slowly sedimenting early interphase cellsExpand
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