Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

Known as: EGFR Tyrosine Kinase Inhibitor, EGFR Inhibitor, EGFR Blocker 
Any tyrosine kinase inhibitor that targets the activity of the epidermal growth factor receptor (EGFR) tyrosine kinase. Inhibition of epidermal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
UNLABELLED First-generation EGFR tyrosine kinase inhibitors (EGFR TKI) provide significant clinical benefit in patients with… (More)
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2013
2013
A secondary epidermal growth factor receptor (EGFR) mutation, the substitution of threonine 790 with methionine (T790M), leads to… (More)
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2013
2013
Since the first description of non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR… (More)
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2012
2012
Epidermal growth factor receptor (EGFR) is one of the most promising targets for non-small cell lung cancer (NSCLC). Our study… (More)
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Highly Cited
2010
Highly Cited
2010
The serine/threonine kinase Akt lies at a critical signaling node downstream of phosphatidylinositol-3-kinase and is important in… (More)
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2010
2010
The epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (ERL) is approved for treatment of non-small-cell lung… (More)
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Highly Cited
2006
Highly Cited
2006
We show that two commonly occurring epidermal growth factor receptor (EGFR) somatic mutations, L858R and an in-frame deletion… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE To evaluate changes in epidermal growth factor receptor (EGFR) phosphorylation and its downstream signaling in tumor and… (More)
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2003
2003
Overexpression of epidermal growth factor receptor (EGFR) is frequently observed in many solid tumor types, including head and… (More)
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1999
1999
Overexpression of the epidermal growth factor (EGF) receptor, a hallmark of aerodigestive squamous cell carcinoma of the head and… (More)
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