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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

Known as: EGFR Tyrosine Kinase Inhibitor, EGFR Inhibitor, EGFR Blocker 
Any tyrosine kinase inhibitor that targets the activity of the epidermal growth factor receptor (EGFR) tyrosine kinase. Inhibition of epidermal… 
National Institutes of Health

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HER1 Antagonists [MoA]Receptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Lung adenocarcinoma metastasis to geographic skull.
2014
2014
Molecular Docking and Rescoring Studies of EGFR Inhibitor Ligands Using Prime
Epidermal growth factor receptor (EGFR) being a priority target in anticancer drug research, it was used for evaluating the… 
Review
2013
Review
2013
Gastric perforation secondary to regression of lung adenocarcinoma after gefitinib treatment.
Case Report In July 2011, an 80-year-old man presented to our hospital with gradual-onset malaise, poor appetite, and weakness of… 
2012
2012
A phase I dose-escalation study of the HSP90 inhibitor AUY922 and erlotinib for patients with EGFR-mutant lung cancer with acquired resistance (AR) to EGFR tyrosine kinase inhibitors (EGFR TKIs).
3083 Background: AUY922 is a highly potent, non-geldanamycin analog, HSP90 inhibitor that degrades mutated EGFR and MET… 
2012
2012
Novel mechanisms of resistance to EGFR inhibitory drugs in non-small cell lung cancer
EGFR activating mutations are present in 10-40% of non-small cell lung cancer. Such mutations render tumour cells sensitive to… 
2010
2010
Economic impact in the management of dermatologic toxicities (dTs) induced by the epidermal growth factor receptor inhibitor (EGFRI) cetuximab in colorectal cancer.
3569 Background: Dermatologic toxicities including rash, xerosis, pruritus, paronychia, alopecia, mucositis and infections occur… 
2009
2009
N-glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
2009
2009
The inhibitory effects of Epidermal growth factor receptor inhibitor (erlotinib) in a mouse model of smoking
Background/Aims: Cigarette smoke may be the main cause of chronic bronchitis. Exposure to cigarette smoke has been reported to… 
2009
2009
Clinical Analysis of 24 Cases Treated Twice or More with Gefitinib for Recurrent Non-small Cell Lung Cancer
背景．Gefitinibは再発非小細胞肺癌に対して18.4%の奏効率を有するが，増悪（PD）後，一旦休薬したのちの再投与（リチャレンジ）に関しての報告は少ない．対象·方法．2002∼2008年の6年間に当施設で再発非小細胞肺癌にGefitinib… 
2008
2008
Minocycline for preventing EGFR inhibitor-induced rash
Introduction: Epidermal growth factor receptor (EGFR) inhibitors are now used relatively commonly in many patients with cancer… 
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