Epidermal Growth Factor Receptor Pathway Substrate 8

Known as: EPS8, Epidermal Growth Factor Receptor Kinase Substrate EPS8 
Epidermal growth factor receptor pathway substrate 8; has a role in normal and neoplastic cell proliferation; contains an SH3 motif. (LocusLink)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
024619932017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Membrane-bound receptors induce biochemical signals to remodel the actin cytoskeleton and mediate cell motility. In association… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
The regulation of filopodia plays a crucial role during neuronal development and synaptogenesis. Axonal filopodia, which are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Dynamic modulation of the actin cytoskeleton is critical for synaptic plasticity, abnormalities of which are thought to… (More)
Is this relevant?
2006
2006
Palladin is a widely expressed phosphoprotein that plays an important role in organizing the actin cytoskeleton. Palladin is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
IRSp53 has been characterized as an adaptor protein that links Rho-family small GTPases, such as Rac, to reorganization of the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Genetic and biochemical evidence demonstrated that Eps8 is involved in the routing of signals from Ras to Rac. This is achieved… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
How epidermal growth factor receptor (EGFR) signalling is linked to EGFR trafficking is largely unknown. Signalling and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The small guanine nucleotide (GTP)-binding protein Rac regulates mitogen-induced cytoskeletal changes and c-Jun amino-terminal… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1995
1995
eps8, a recently identified tyrosine kinase substrate, has been shown to augment epidermal growth factor (EGF) responsiveness… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
A method which allows direct cloning of intracellular substrates for receptor tyrosine kinases (RTKs) was developed. By applying… (More)
Is this relevant?