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Enzyme-Linked Immunospot Assay

Known as: ELISPOT, Immunospot Assays, Enzyme-Linked, Immunospot Assay, Enzyme-Linked 
A highly sensitive immunoassay capable of detecting secreted materials from individual cells upon activation. If the material of interest is secreted… 
National Institutes of Health

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Clinical Data Interchange Standards Consortium TerminologyEnzyme-Linked Immunosorbent Assaystandards characteristics

Papers overview

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Highly Cited
2007
Highly Cited
2007
Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: effects of dosage and route on safety and immunogenicity.
Highly Cited
2004
Highly Cited
2004
Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells.
Anti-CD154 (CD40L) monoclonal antibody (mAb) plus bone marrow transplantation (BMT) in mice receiving CD8 cell-depleting mAb… 
Highly Cited
2002
Highly Cited
2002
Generation of CD8+ T Cell Memory in Response to Low, High, and Excessive Levels of Epitope1
The magnitude of a virus-specific memory CTL population can dramatically influence the outcome of secondary infections, yet… 
Highly Cited
2000
Highly Cited
2000
Quantitation of antigen-reactive T cells in peripheral blood by IFNgamma-ELISPOT assay and chromium-release assay: a four-centre comparative trial.
Highly Cited
2000
Highly Cited
2000
Th1-like dominance in high-risk first-degree relatives of Type I diabetic patients
Aims/hypothesis. The humoral part of the immune system, including autoantibodies, is known to predict manifest Type I (insulin… 
Highly Cited
1997
Highly Cited
1997
Paternal Leukocytes Selectively Increase Secretion of IL‐4 in Peripheral Blood During Normal Pregnancies: Demonstrated by a Novel One‐Way MLC Measuring Cytokine Secretion
PROBLEM: It has been proposed that immune responses in normal pregnancy are Th2‐like, thereby protecting the fetus and placenta… 
Highly Cited
1995
Highly Cited
1995
Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and beta-galactosidase.
One major concern about using adenoviral vectors for repetitive gene delivery to lung epithelial cells is the induction of an… 
Highly Cited
1993
Highly Cited
1993
Cytokine synthesis by intestinal intraepithelial lymphocytes. Both gamma/delta T cell receptor-positive and alpha/beta T cell receptor-positive T cells in the G1 phase of cell cycle produce IFN-gamma…
Murine intestinal intraepithelial lymphocytes (IEL) have been shown to contain subsets of alpha/beta TCR+ and gamma/delta TCR+ T… 
Highly Cited
1992
Highly Cited
1992
Reverse ELISPOT assay for clonal analysis of cytokine production. II. Enumeration of interleukin-1-secreting cells by amplified (avidin-biotin anti-peroxidase) assay.
Highly Cited
1985
Highly Cited
1985
Evidence for a Common Mucosal Immune System in Humans
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